乙基2-异丙基-3-氧代-4-苯基丁酸酯合成路线 （共 10 条）
反应条件
zinc in tetrahydrofuran 0.166667 h; Heating;
参考文献
Danel, Krzysztof; Larsen, Erik; Pedersen, Erik B.; Vestergaard, Bent F.; Nielsen, Claus
Journal of Medicinal Chemistry, 1996 , vol. 39, # 12 p. 2427 - 2431
反应条件
thiourea; sodium ethanolate
参考文献
Sbardella, Gianluca; Mai, Antonello; Artico, Marino; Massa, Silvio; Marceddu, Tiziana; Vargiu, Laura; Marongiu, Maria Elena; La Colla, Paolo
Medicinal Chemistry Research, 2000 , vol. 10, # 1 p. 30 - 39
反应条件
tetrabutylammomium bromide; potassium carbonate in N,N-dimethyl-formamide T=20°C; 12 h; TemperatureSolvent;
参考文献
Li, Li; Ma, Liying; Wang, Xiaowei; Liu, Junyi
Journal of Heterocyclic Chemistry, 2013 , vol. 50, # 1 p. 164 - 168
反应条件
1.1: pyridine / dichloromethane / 2 h / 0 - 20 °C 1.2: 2.5 h / |Reflux 2.1: potassium carbonate; tetrabutylammomium bromide / N,N-dimethyl-formamide / 12 h / 20 °C View Scheme
参考文献
Li, Li; Ma, Liying; Wang, Xiaowei; Liu, Junyi
Journal of Heterocyclic Chemistry, 2013 , vol. 50, # 1 p. 164 - 168
反应条件
1: zinc 2: aq. HCl View Scheme
参考文献
Sbardella, Gianluca; Mai, Antonello; Artico, Marino; Massa, Silvio; Marceddu, Tiziana; Vargiu, Laura; Marongiu, Maria Elena; La Colla, Paolo
Medicinal Chemistry Research, 2000 , vol. 10, # 1 p. 30 - 39
反应条件
ethanol; sodium ethanolate
参考文献
Soliman; West
Journal of the Chemical Society, 1944 , p. 53
反应条件
sodium ethanolate in ethanol
参考文献
Sbardella, Gianluca; Mai, Antonello; Artico, Marino; Massa, Silvio; Marceddu, Tiziana; Vargiu, Laura; Marongiu, Maria Elena; La Colla, Paolo
Medicinal Chemistry Research, 2000 , vol. 10, # 1 p. 30 - 39
反应条件
1: 72 percent / EtONa / ethanol / 6 h / Heating 2: 1.) bis(trimethylsilyl)acetamide / 1.) CHCl3, RT, 10 min, 2.) CHCl3, RT View Scheme
参考文献
Li, Li; Ma, Liying; Wang, Xiaowei; Liu, Junyi
Journal of Heterocyclic Chemistry, 2013 , vol. 50, # 1 p. 164 - 168
反应条件
sodium ethanolate in ethanol 6 h; Heating;
参考文献
Danel, Krzysztof; Larsen, Erik; Pedersen, Erik B.; Vestergaard, Bent F.; Nielsen, Claus
Journal of Medicinal Chemistry, 1996 , vol. 39, # 12 p. 2427 - 2431
反应条件
1: sodium ethanolate / ethanol / 6 h / |Reflux 2: chloroacetic acid / water / 24 h / |Reflux View Scheme
参考文献
Li, Li; Ma, Liying; Wang, Xiaowei; Liu, Junyi
Journal of Heterocyclic Chemistry, 2013 , vol. 50, # 1 p. 164 - 168
