hydrogenchloride in methanol T=10 - 20°C; 0.5 h;

<b>Multi-step reaction with 2 steps<br /> </b>1.1: 74.5 g / imidazole / dimethylformamide / 20 h / 50 &deg;C<br />2.1: n-BuLi / diethyl ether; hexane / 0.5 h / 0 - 10 &deg;C<br />2.2: 70.0 g / diethyl ether; hexane / 1 h<br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: 96 percent / DBU<br />2: 1.) BuLi / 1.) THF, -78 deg C<br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1.1: 1H-imidazole / N,N-dimethyl-formamide / 2 h / 20 &deg;C<br />2.1: n-butyllithium / tetrahydrofuran; hexane / 0.75 h / -78 &deg;C<br />2.2: 1.25 h / -78 &deg;C<br /> <br /> &nbsp;