(5-甲氧基-1-甲基-1H-吲哚-3-基)乙腈合成路线 （共 3 条）
反应条件
sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate in dichloromethane T=30°C; 48 h;
参考文献
Morales-Rios, Martha S.; Santos-Sanchez, Norma F.; Mora-Perez, Yolanda; Joseph-Nathan, Pedro
Heterocycles, 2004 , vol. 63, # 5 p. 1131 - 1142
反应条件
1: diethylamine; acetic acid / H2O / 3 h / 20 °C 2: 1.08 g / MeI / methanol; H2O / 10 h / 20 °C 3: 0.53 g / aq. KOH / dimethylformamide / 0 - 20 °C View Scheme
参考文献
Tsotinis, Andrew; Vlachou, Margarita; Papahatjis, Demetris P.; Calogeropoulou, Theodora; Nikas, Spyros P.; Garratt, Peter J.; Piccio, Vincent; Vonhoff, Stefan; Davidson, Kathryn; Teh, Muy-Teck; Sugden, David
Journal of Medicinal Chemistry, 2006 , vol. 49, # 12 p. 3509 - 3519
反应条件
1: 1.08 g / MeI / methanol; H2O / 10 h / 20 °C 2: 0.53 g / aq. KOH / dimethylformamide / 0 - 20 °C View Scheme
参考文献
Tsotinis, Andrew; Vlachou, Margarita; Papahatjis, Demetris P.; Calogeropoulou, Theodora; Nikas, Spyros P.; Garratt, Peter J.; Piccio, Vincent; Vonhoff, Stefan; Davidson, Kathryn; Teh, Muy-Teck; Sugden, David
Journal of Medicinal Chemistry, 2006 , vol. 49, # 12 p. 3509 - 3519
