2-氨基-3-羟基苯甲酸甲酯合成路线 (共 20 条)
反应条件
1: K2S2O8; aqueous KOH 2: aqueous HCl 3: methanol. HCl View Scheme
参考文献
Journal of the Chemical Society, , p. 980,984
参考文献
Liebigs Annalen der Chemie, , # 8 p. 1515 - 1518
反应条件
pyridine 2 h; Heating / reflux;
参考文献
AMR TECHNOLOGY, INC.
Patent: US2008/255114 A1, 2008 ;
Location in patent: Page/Page column 7 ;
参考文献
LEAD THERAPEUTICS, INC.
Patent: US2009/197863 A1, 2009 ;
Location in patent: Page/Page column 66 ;
反应条件
pyridinium p-toluenesulfonate; triethylamine in xylene 16 h; Heating;
参考文献
Goldstein, Steven W.; Dambeck, Paul J.
Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 2 p. 335 - 336
反应条件
pyridine; toluene-4-sulfonic acid; triethylamine in xylene Reflux;
参考文献
FIBROTECH THERAPEUTICS PTY LTD; WILLIAMS, Spencer John; ZAMMIT, Steven; KELLY, Darren James
Patent: WO2011/47432 A1, 2011 ;
Location in patent: Page/Page column 107 ;
反应条件
triethylamine in m-xylene
参考文献
Newcastle University Ventures Limited
Patent: US5756510 A1, 1998 ;
反应条件
N-benzyl-N,N,N-triethylammonium chloride; sodium hydrogencarbonate in chloroform T=55°C; 5 h;
参考文献
ACTELION PHARMACEUTICALS LTD
Patent: WO2009/16560 A2, 2009 ;
Location in patent: Page/Page column 40; 72 ;
WO 2009/016560 A2
反应条件
p-benozquinone in ethanol T=40°C; 24 h;
参考文献
Jabri, Salman Y.; Overman, Larry E.
Journal of Organic Chemistry, 2013 , vol. 78, # 17 p. 8766 - 8788
参考文献
LEAD THERAPEUTICS, INC.
Patent: US2009/197863 A1, 2009 ;
Location in patent: Page/Page column 67 ;