2-甲基-4(3H)-喹唑酮合成路线 （共 123 条）
反应条件
T=180°C; Cyclization; 1 h;
参考文献
Ramana; Sundaram; Eswara Yuvaraj; Ganesh Babu
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1999 , vol. 38, # 8 p. 905 - 908
反应条件
caesium carbonate in N,N-dimethyl-formamide T=20°C; 10 h; Inert atmosphereSealed tube;
参考文献
Yu, Lin; Wang, Min; Li, Pinhua; Wang, Lei
Applied Organometallic Chemistry, 2012 , vol. 26, # 11 p. 576 - 582,7
反应条件
caesium carbonate in N,N-dimethyl-formamide T=20°C; 10 h; Inert atmosphereSealed tube; Reagent/catalystSolvent;
参考文献
Yu, Lin; Wang, Min; Li, Pinhua; Wang, Lei
Applied Organometallic Chemistry, 2012 , vol. 26, # 11 p. 576 - 582,7
反应条件
ammonium hydroxide in ethanol T=20°C; Substitution; 48 h;
参考文献
Santagati, Natale Alfredo; Bousquet, Ennio; Spadaro, Angelo; Ronsisvalle, Giuseppe
Farmaco, 1999 , vol. 54, # 11-12 p. 780 - 784
反应条件
1: With caesium carbonate; L-proline in N,N-dimethyl-formamide T=20°C; 0.5 h; Inert atmosphere; 2: With copper(l) iodide in N,N-dimethyl-formamide T=20 - 80°C; 20 h; Inert atmosphere;
参考文献
Huang, Cheng; Fu, Yuan; Fu, Hua; Jiang, Yuyang; Zhao, Yufen
Chemical Communications, 2008 , # 47 p. 6333 - 6335
反应条件
1: With caesium carbonate; L-proline in N,N-dimethyl-formamide T=20°C; 0.5 h; Inert atmosphere; 2: With copper(l) iodide in N,N-dimethyl-formamide T=20 - 80°C; 16 h; Inert atmosphere;
参考文献
Huang, Cheng; Fu, Yuan; Fu, Hua; Jiang, Yuyang; Zhao, Yufen
Chemical Communications, 2008 , # 47 p. 6333 - 6335
反应条件
hydrogen; palladium on activated charcoal in ethanol P=1551.4 Torr; 0.9 h;
参考文献
Lin, Yang-i; Lang, S. A.
Journal of Heterocyclic Chemistry, 1980 , vol. 17, p. 1273 - 1276
反应条件
hydrogenchloride; acetic acid in water T=0°C; Heating / reflux;
参考文献
WO2006/32138 A1, ;
Page/Page column 26 ;
反应条件
1-methyl-pyrrolidin-2-one; tetrakis(triphenylphosphine) palladium(0); potassium carbonate T=100°C; 24 h;
参考文献
Journal of the American Chemical Society, , vol. 111, # 10 p. 3725 - 3727
反应条件
caesium carbonate in N,N-dimethyl-formamide T=50°C; 10 h; Inert atmosphereSealed tube;
参考文献
Yu, Lin; Wang, Min; Li, Pinhua; Wang, Lei
Applied Organometallic Chemistry, 2012 , vol. 26, # 11 p. 576 - 582,7
