2-甲基-4(3H)-喹唑酮合成路线 (共 123 条)
反应条件
lead(IV) acetate; 1-hexene in dichloromethane 0.25 h; Ambient temperature;
参考文献
Atkinson, Robert S.; Malpass, John R.; Skinner, Karen L.; Woodthorpe, Katherine L.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 8 p. 1905 - 1912
参考文献
Bajardi, Maria Luisa; Daidone, Giuseppe; Raffa, Demetrio; Plescia, Salvatore
Heterocycles, 1986 , vol. 24, # 5 p. 1367 - 1372
反应条件
T=180°C; 0.333333 h;
参考文献
Journal of Organic Chemistry, , vol. 49, # 8 p. 1449 - 1450
反应条件
lead(IV) acetate in dichloromethane 0.25 h; Ambient temperature;
参考文献
Atkinson, Robert S.; Malpass, John R.; Skinner, Karen L.; Woodthorpe, Katherine L.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 8 p. 1905 - 1912
反应条件
in ethanol Heating; Product distribution;
参考文献
Scheiner; Frank; Giusti; et al.
Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 6 p. 1817 - 1824
反应条件
1: 140 °C 2: 30percent aq. NH3 / Ambient temperature 3: 2N aq. NaOH / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 8, # 5 p. 505 - 510
反应条件
1: 1) BuLi / 1) Et2O, hexane, O deg C, 15 min, 2) Et2O, reflux, 1 h 2: 1) BuLi / 1) THF, hexane, -30 deg C, 2) THF, a) -30 deg C to r.t., b) reflux, 15 min View Scheme
参考文献
Synthesis, , # 11 p. 1009 - 1010
反应条件
potassium hydroxide 120 h; Ambient temperature;
参考文献
Heterocycles, , vol. 24, # 5 p. 1367 - 1372
反应条件
n-butyllithium 1) THF, hexane, -30 deg C, 2) THF, a) -30 deg C to r.t., b) reflux, 15 min; Yield given. Multistep reaction;
参考文献
Synthesis, , # 11 p. 1009 - 1010
反应条件
1: 1.) Fe, glacial acetic acid / 1.) 70 deg C, 2 h, 2.) MeOH, reflux, 3 h 2: 10percent aq. KOH / 120 h / Ambient temperature View Scheme
参考文献
Heterocycles, , vol. 24, # 5 p. 1367 - 1372