2,3-二甲基-3H-喹唑啉-4-酮合成路线 （共 31 条）
反应条件
carbon monoxide; tri-ruthenium(0)dodecacarbonyl in 1,4-dioxane T=140°C; P=30400 Torr; 16 h;
参考文献
Akazome, Motohiro; Kondo, Teruyuki; Watanabe, Yoshihisa
Journal of Organic Chemistry, 1993 , vol. 58, # 2 p. 310 - 312
反应条件
potassium hydroxide in tetrahydrofuran; water T=50 - 60°C; 18 h;
参考文献
Rathman, Terry L.; Sleevi, Mark C.; Krafft, Marie E.; Wolfe, James F.
Journal of Organic Chemistry, 1980 , vol. 45, # 11 p. 2169 - 2176
反应条件
1: 2-methyl-4-oxo-3,4-dihydroquinazoline With sodium hydride in N,N-dimethyl-formamide; mineral oil T=0°C; 1 h; Inert atmosphere; 2: methyl iodide in N,N-dimethyl-formamide; mineral oil T=25°C; 12 h; Inert atmosphere;
参考文献
Takemura, Noriaki; Kuninobu, Yoichiro; Kanai, Motomu
Organic and Biomolecular Chemistry, 2014 , vol. 12, # 16 p. 2528 - 2532
反应条件
silica gel in ethyl acetate T=20°C; Cyclization;
参考文献
He; Snider
Journal of Organic Chemistry, 1999 , vol. 64, # 4 p. 1397 - 1399
反应条件
PPh3.Br2 in dichloromethane 3 h; Heating;
参考文献
Mazurkiewicz, Roman
Monatshefte fuer Chemie, 1989 , vol. 120, p. 973 - 980
反应条件
triphenylphosphine in xylene 2 h; Ambient temperature;
参考文献
Takeuchi, Hisato; Eguchi, Shoji
Tetrahedron Letters, 1989 , vol. 30, # 25 p. 3313 - 3314
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Takeuchi, Hisato; Hagiwara, Satoshi; Eguchi, Shoji
Tetrahedron, 1989 , vol. 45, # 20 p. 6375 - 6386
反应条件
copper(l) iodide; potassium carbonate in N,N-dimethyl-formamide T=80°C; 6 h; Inert atmosphere;
参考文献
Zhou, Jing; Fu, Liangbing; Lv, Man; Liu, Jinsong; Pei, Duanqing; Ding, Ke
Synthesis, 2008 , # 24 art. no. F18308SS, p. 3974 - 3980
反应条件
trifluorormethanesulfonic acid in dichloromethane T=20°C; 40 h;
参考文献
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, , vol. 42, # 2 p. 393 - 396
反应条件
N,N-dimethyl-cyclohexylamine; phosphorus pentoxide T=150°C; 0.333333 h; further temperature;
参考文献
Nielsen, Knud Erik; Pedersen, Erik B.
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1980 , vol. 34, # 9 p. 637 - 642
反应条件
hydrogenchloride in 1,2-dichloro-ethane T=25°C; 120 h; other times and temp., other molar ratios, other reagent: HBr; MechanismProduct distribution;
参考文献
Mazurkiewicz, Roman
Monatshefte fuer Chemie, 1989 , vol. 120, p. 973 - 980
