1-(1,4-二氧杂-8-氮杂螺[4.5]癸-8-基)乙酮合成路线 （共 3 条）
反应条件
hydrogenchloride in methanol T=20°C; 19 h;
参考文献
Kobashi, Seiichi; Kubo, Hajime; Yamauchi, Takayasu; Higashiyama, Kimio
Biological and Pharmaceutical Bulletin, 2002 , vol. 25, # 8 p. 1030 - 1034
反应条件
1: LiAlH4 / diethyl ether / 18 h / 0 °C 2: 5percent HCl / acetone / 12 h / Heating View Scheme
参考文献
Anderson, J. Edgar; Ijeh, Anthony I.; Storch, Christine; Casarini, Daniele; Lunazzi, Lodovico
Journal of Organic Chemistry, 1998 , vol. 63, # 10 p. 3310 - 3317
反应条件
1: 70 percent / HCl / methanol / 19 h / 20 °C
2: 53 percent / NaBH3Cn / ethanol; HCl / 96 h / 20 °C / pH 6
View Scheme
参考文献
Kobashi, Seiichi; Kubo, Hajime; Yamauchi, Takayasu; Higashiyama, Kimio
Biological and Pharmaceutical Bulletin, 2002 , vol. 25, # 8 p. 1030 - 1034
