1: 99 percent / tetrahydrofuran; H2O / 5 h / 20 °C 2: 95 percent / Na2CO3 / ethanol / 24 h / 30 °C 3: 94 percent / aq. 6N HCl / 14 h / Heating 4: 100 percent / CH3COCl / 12 h / 60 °C 5: 85 percent / DIEA / acetonitrile / 24 h / 50 °C 6: 91 percent / (COCl)2; DMSO / CH2Cl2 / 0.33 h / -78 °C 7: 83 percent / aq. LiOH / methanol / 12 h / 70 °C 8: (COCl)2 9: Et3N; N-methyl-2-chloropyridinium iodide / CH2Cl2 / 12 h / Heating 10: Bu3SnH / CH2Cl2 / 2 h / Irradiation View Scheme