4-溴-2-乙基-7-甲氧基-2,3-二氢-1H-茚-1-酮合成路线 （共 4 条）
反应条件
1: 24 percent / C3H7COONa / 150 °C 2: H2 / 10percent Pd/C / methanol / 2280 Torr 3: Br2, AcOH / 2.5 h / Ambient temperature 4: 30.0 g / polyphosphoric acid / 2.5 h / 100 °C View Scheme
参考文献
Hagishita, Sanji; Yamada, Masaaki; Shirahase, Kazuhiro; Okada, Toshihiko; Murakami, Yasushi; Ito, Yuji; Matsuura, Takaharu; Wada, Masaaki; Kato, Toshiyuki; Ueno, Masahiko; Chikazawa, Yukiko; Yamada, Katsutoshi; Ono, Takashi; Teshirogi, Isao; Ohtani, Mitsuaki
Journal of Medicinal Chemistry, 1996 , vol. 39, # 19 p. 3636 - 3658
反应条件
1: H2 / 10percent Pd/C / methanol / 2280 Torr 2: Br2, AcOH / 2.5 h / Ambient temperature 3: 30.0 g / polyphosphoric acid / 2.5 h / 100 °C View Scheme
参考文献
Hagishita, Sanji; Yamada, Masaaki; Shirahase, Kazuhiro; Okada, Toshihiko; Murakami, Yasushi; Ito, Yuji; Matsuura, Takaharu; Wada, Masaaki; Kato, Toshiyuki; Ueno, Masahiko; Chikazawa, Yukiko; Yamada, Katsutoshi; Ono, Takashi; Teshirogi, Isao; Ohtani, Mitsuaki
Journal of Medicinal Chemistry, 1996 , vol. 39, # 19 p. 3636 - 3658
参考文献
Hagishita, Sanji; Yamada, Masaaki; Shirahase, Kazuhiro; Okada, Toshihiko; Murakami, Yasushi; Ito, Yuji; Matsuura, Takaharu; Wada, Masaaki; Kato, Toshiyuki; Ueno, Masahiko; Chikazawa, Yukiko; Yamada, Katsutoshi; Ono, Takashi; Teshirogi, Isao; Ohtani, Mitsuaki
Journal of Medicinal Chemistry, 1996 , vol. 39, # 19 p. 3636 - 3658
反应条件
1: Br2, AcOH / 2.5 h / Ambient temperature 2: 30.0 g / polyphosphoric acid / 2.5 h / 100 °C View Scheme
参考文献
Hagishita, Sanji; Yamada, Masaaki; Shirahase, Kazuhiro; Okada, Toshihiko; Murakami, Yasushi; Ito, Yuji; Matsuura, Takaharu; Wada, Masaaki; Kato, Toshiyuki; Ueno, Masahiko; Chikazawa, Yukiko; Yamada, Katsutoshi; Ono, Takashi; Teshirogi, Isao; Ohtani, Mitsuaki
Journal of Medicinal Chemistry, 1996 , vol. 39, # 19 p. 3636 - 3658
