2-(2-溴乙氧基)四氢-2H-吡喃合成路线 （共 25 条）
反应条件
pyridinium p-toluenesulfonate in dichloromethane
参考文献
Collection of Czechoslovak Chemical Communications, , vol. 69, # 10 p. 1843 - 1876
反应条件
toluene-4-sulfonic acid in hexane; chloroform; ethyl acetate
反应条件
toluene-4-sulfonic acid in dichloromethane T=0°C; 3 h;
参考文献
Journal of Medicinal Chemistry, , vol. 54, # 21 p. 7693 - 7704
反应条件
1: tetrahydrofuran; hexamethylphosphoric acid triamide / 3 h / 0 - 25 °C 2: KF / dimethylformamide / 0.5 h / 55 °C View Scheme
参考文献
Stefani, Helio A.; Cardoso, Lincoln D. G.; Valduga, Claudete J.; Zeni, Gilson
Phosphorus, Sulfur and Silicon and Related Elements, 2001 , vol. 171-172, p. 167 - 172
反应条件
pyridinium p-toluenesulfonate; lithium diisopropyl amide 1.) THF, 2.) MeOH; Yield given. Multistep reaction;
参考文献
Oda, Mitsunori; Kamata, Yoshitaka; Nishii, Satoshi; Miyatake, Ryuta; Kuroda, Shigeyasu; Oda, Masaji
Recueil des Travaux Chimiques des Pays-Bas-Journal of the Royal Netherlands, 1996 , vol. 115, # 10 p. 445 - 446
反应条件
1: With sodium hydride in N,N-dimethyl-formamide T=20°C; 17 h; 2: With hydrogenchloride; methanol in 1,4-dioxane T=20°C; 16 h;
参考文献
WO2008/81012 A1, ;
Page/Page column 43-44 ;
WO 2008/081012 A1
反应条件
hydrogen Multistep reaction;
参考文献
Steiner, B.; Schumann, D.; Hoffmann, H.
Organic Mass Spectrometry, 1983 , vol. 18, # 8 p. 345 - 349
反应条件
sodium hydroxide; tetra-n-butyl-ammonium sulfate in benzene T=50°C; 6 h;
参考文献
Journal of Organic Chemistry, , vol. 52, # 26 p. 5700 - 5704
反应条件
2,2'-azo-bisisobutyronitrile in toluene
T=80°C;
参考文献
Keck, Gary E.; Enholm, Eric J.; Yates, John B.; Wiley, Michael R.
Tetrahedron, 1985 , vol. 41, # 19 p. 4079 - 4094
反应条件
2,2'-azo-bisisobutyronitrile in toluene
T=80°C; 8 h;
参考文献
Keck, Gary E.; Yates, John B.
Journal of the American Chemical Society, 1982 , vol. 104, # 21 p. 5829 - 5831
