2-氧代-1,2,3,4-四氢喹啉-6-羧酸甲酯合成路线 （共 5 条）
反应条件
potassium carbonate; [pentamethylcyclopentadienylRhCl2]2 in acetone T=100°C; 20 h;
参考文献
Fujita, Ken-Ichi; Takahashi, Yoshinori; Owaki, Maki; Yamamoto, Kazunari; Yamaguchi, Ryohei
Organic Letters, 2004 , vol. 6, # 16 p. 2785 - 2788
反应条件
potassium carbonate; bis(dibenzylideneacetone)-palladium(0); 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl in N,N-dimethyl-formamide T=95°C; 12 h; Inert atmosphere;
参考文献
Tsuritani, Takayuki; Yamamoto, Yuhei; Kawasaki, Masashi; Mase, Toshiaki
Organic Letters, 2009 , vol. 11, # 5 p. 1043 - 1045
反应条件
1: 66 percent / Et3N; CuI / PdCl2(PPh3)2 / 4.5 h / 20 °C 2: 48 percent / Et3N; CuI / PdCl2(PPh3)2 / 4.5 h / 20 °C 3: 97 percent / K2CO3 / [pentamethylcyclopentadienylRhCl2]2 / acetone / 20 h / 100 °C View Scheme
参考文献
Fujita, Ken-Ichi; Takahashi, Yoshinori; Owaki, Maki; Yamamoto, Kazunari; Yamaguchi, Ryohei
Organic Letters, 2004 , vol. 6, # 16 p. 2785 - 2788
反应条件
hydrogenchloride; water in N,N-dimethyl-formamide
参考文献
Tsuritani, Takayuki; Yamamoto, Yuhei; Kawasaki, Masashi; Mase, Toshiaki
Organic Letters, 2009 , vol. 11, # 5 p. 1043 - 1045
反应条件
in tetrahydrofuran; methanol; water; ethyl acetate
参考文献
Fujisawa Pharmaceutical Co., Ltd.
Patent: US6083961 A1, 2000 ;
