4-硝基苯酚三氟甲基磺酸酯合成路线 （共 131 条）
反应条件
tetrabutylammomium bromide; caesium carbonate; triphenylphosphine; palladium dichloride in N,N-dimethyl acetamide
T=90°C; 1 h;
参考文献
Rao, Maddali L.N.; Jadhav, Deepak N.; Banerjee, Debasis
Tetrahedron, 2008 , vol. 64, # 24 p. 5762 - 5772
反应条件
palladium diacetate in ethanol
T=95°C; 0.25 h; microwave irradiation;
参考文献
Kabalka, George W.; Zhou, Li-Li; Naravane, Abhijit
Tetrahedron Letters, 2006 , vol. 47, # 38 p. 6887 - 6889
反应条件
lithium chloride; bis-triphenylphosphine-palladium(II) chloride in tetrahydrofuran; N,N-dimethyl-formamide
T=80°C; Stille coupling; 22 h;
参考文献
Hoshino, Masahide; Degenkolb, Peter; Curran, Dennis P.
Journal of Organic Chemistry, 1997 , vol. 62, # 24 p. 8341 - 8349
反应条件
bis-triphenylphosphine-palladium(II) chloride; lithium chloride in tetrahydrofuran; N,N-dimethyl-formamide
T=80°C; 22 h;
参考文献
Curran, Dennis P.; Hoshino, Masahide
Journal of Organic Chemistry, 1996 , vol. 61, # 19 p. 6480 - 6481
反应条件
dicyclohexyl(2′,6′-dimethoxybiphenyl-2-yl)phosphine; tripotassium phosphate monohydrate; palladium diacetate in toluene
Suzuki coupling;
参考文献
O'Connell, Daniel P.; Leblanc, Daniel F.; Cromley, Debra; Billheimer, Jeffrey; Rader, Daniel J.; Bachovchin, William W.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 3 p. 1397 - 1401
反应条件
potassium carbonate; tetrakis(triphenylphosphine) palladium(0) in acetonitrile
T=120°C; 3 h;
参考文献
Arcadi, Antonio; Cacchi, Sandro; Fabrizi, Giancarlo; Parisi, Luca M.
Tetrahedron Letters, 2004 , vol. 45, # 11 p. 2431 - 2434
反应条件
N-ethyl-N,N-diisopropylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide in N,N-dimethyl-formamide
T=45°C; 48 h;
参考文献
Soellner, Matthew B.; Rawls, Katherine A.; Grundner, Christoph; Alber, Tom; Ellman, Jonathan A.
Journal of the American Chemical Society, 2007 , vol. 129, # 31 p. 9613 - 9615
反应条件
7-methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene on polystyrene.HL in acetonitrile
T=80°C; Esterification;
参考文献
Boisnard, Sabine; Chastanet, Jaqueline; Zhu, Jieping
Tetrahedron Letters, 1999 , vol. 40, # 42 p. 7469 - 7472
反应条件
1: dicyclohexyl(2′,6′-dimethoxybiphenyl-2-yl)phosphine; tripotassium phosphate monohydrate; palladium diacetate / toluene
2: 10 palladium on activated charcoal; hydrogen / ethanol
3: hydrogenchloride; sodium nitrite / water / Cooling with ice
4: dicyclohexyl(2′,6′-dimethoxybiphenyl-2-yl)phosphine; palladium diacetate; triethylamine / 1,4-dioxane / 80 °C
View Scheme
参考文献
O'Connell, Daniel P.; Leblanc, Daniel F.; Cromley, Debra; Billheimer, Jeffrey; Rader, Daniel J.; Bachovchin, William W.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 3 p. 1397 - 1401
反应条件
tris(dibenzylideneacetone)dipalladium (0); tris-(o-tolyl)phosphine; lithium chloride in N,N-dimethyl-formamide
T=20°C; cross-coupling; 3 h;
参考文献
Dexter, Charles S.; Jackson, Richard F.W.; Elliott, Jason
Tetrahedron, 2000 , vol. 56, # 26 p. 4539 - 4540
