4-硝基苯酚三氟甲基磺酸酯合成路线 （共 131 条）
反应条件
dicyclohexyl(2′,6′-dimethoxybiphenyl-2-yl)phosphine; tripotassium phosphate monohydrate; palladium diacetate in toluene
Suzuki coupling;
参考文献
O'Connell, Daniel P.; Leblanc, Daniel F.; Cromley, Debra; Billheimer, Jeffrey; Rader, Daniel J.; Bachovchin, William W.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 3 p. 1397 - 1401
反应条件
7-methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene on polystyrene.HL in acetonitrile
T=80°C; Esterification;
参考文献
Boisnard, Sabine; Chastanet, Jaqueline; Zhu, Jieping
Tetrahedron Letters, 1999 , vol. 40, # 42 p. 7469 - 7472
反应条件
tetrakis(triphenylphosphine) palladium(0) in toluene
T=80°C; 3 h; Inert atmosphere;
参考文献
Bello, Charles S.; Schmidt-Leithoff, Joachim
Tetrahedron Letters, 2012 , vol. 53, # 46 p. 6230 - 6235,6
反应条件
1: tetrakis(dimethylamino)diboron; 3-hydroxy-2,2-dimethylpropanol With potassium acetate in toluene
T=80°C;
2: 4-nitrophenyl trifluoromethanesulphonate With tetrakis(triphenylphosphine) palladium(0) in toluene
T=80°C; 22 h;
参考文献
Bello, Charles S.; Schmidt-Leithoff, Joachim
Tetrahedron Letters, 2012 , vol. 53, # 46 p. 6230 - 6235,6
反应条件
1: dicyclohexyl(2′,6′-dimethoxybiphenyl-2-yl)phosphine; tripotassium phosphate monohydrate; palladium diacetate / toluene
2: 10 palladium on activated charcoal; hydrogen / ethanol
View Scheme
参考文献
O'Connell, Daniel P.; Leblanc, Daniel F.; Cromley, Debra; Billheimer, Jeffrey; Rader, Daniel J.; Bachovchin, William W.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 3 p. 1397 - 1401
反应条件
dicyclohexyl(2′,6′-dimethoxybiphenyl-2-yl)phosphine; tripotassium phosphate monohydrate; palladium diacetate in toluene
Suzuki coupling;
参考文献
O'Connell, Daniel P.; Leblanc, Daniel F.; Cromley, Debra; Billheimer, Jeffrey; Rader, Daniel J.; Bachovchin, William W.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 3 p. 1397 - 1401
参考文献
de Oliveira Baptista,M.J.V.; Widdowson,D.A.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1978 , p. 295 - 298
反应条件
2,2'-bis(di-p-tolyl-phosphino)-1,1'-binaphthyl; copper(I) oxide; 1,10-phenanthroline; palladium (II) 2,4-pentanedionate in 1-methyl-pyrrolidin-2-one
T=50 - 190°C; P=3375.34 Torr; Inert atmosphereMicrowave irradiation;
参考文献
Goossen, Lukas J.; Linder, Christophe; Rodriguez, Nuria; Lange, Paul P.
Chemistry - A European Journal, 2009 , vol. 15, # 37 p. 9336 - 9349
反应条件
palladium diacetate in ethanol
T=95°C; 0.25 h; microwave irradiation;
参考文献
Kabalka, George W.; Zhou, Li-Li; Naravane, Abhijit
Tetrahedron Letters, 2006 , vol. 47, # 38 p. 6887 - 6889
反应条件
caesium carbonate; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene; tris(dibenzylideneacetone)dipalladium (0) in toluene
T=120°C; 20 h;
参考文献
Cacchi, Sandro; Fabrizi, Giancarlo; Goggiamani, Antonella; Parisi, Luca M.; Bernini, Roberta
Journal of Organic Chemistry, 2004 , vol. 69, # 17 p. 5608 - 5614
