7-羟基-2,2-二甲基-苯并二氢吡喃-4-酮合成路线 （共 37 条）
反应条件
phosphorous pentoxide in methanesulfonic acid T=70°C; Friedel-Crafts Acylation; 0.333333 h; Inert atmosphereMicrowave irradiation;
参考文献
Morales, Paula; Azofra, Luis Miguel; Cumella, Jose; Hernandez-Folgado, Laura; Roldan, Maria; Alkorta, Ibon; Jagerovic, Nadine
Arkivoc, 2014 , vol. 2014, # 2 p. 319 - 332
反应条件
phosphorous pentoxide in methanesulfonic acid T=70°C; Friedel-Crafts Acylation; 1 h; Inert atmosphereMicrowave irradiation;
参考文献
Arkivoc, , vol. 2014, # 2 p. 319 - 332
反应条件
piperidine 0.166667 h; Neat (no solvent)Microwave irradiation;
参考文献
Tripathi; Koul; Taneja
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2009 , vol. 48, # 2 p. 301 - 304
反应条件
sodium hydroxide 1 h; Ambient temperature;
参考文献
Seboek, Peter; Jekoe, Jozsef; Timar, Tibor; Jaszberenyi, Joseph Cs.
Heterocycles, 1994 , vol. 38, # 9 p. 2099 - 2114
反应条件
hydrogen bromide; acetic acid T=100°C;
参考文献
WO2012/110860 A1, ;
Page/Page column 60 ;
WO 2012/110860 A1
反应条件
sodium hydroxide; hydrogen; nickel in ethanol P=3800 Torr; 1 h; Ambient temperature; Yield given. Yields of byproduct given;
参考文献
Journal of Organic Chemistry, , vol. 59, # 21 p. 6318 - 6321
反应条件
sodium hydroxide; hydrogen; nickel in ethanol P=3800 Torr; 1 h; Ambient temperature; Yield given. Yields of byproduct given;
参考文献
Journal of Organic Chemistry, , vol. 59, # 21 p. 6318 - 6321
反应条件
in water; pyridine hydrochloride
参考文献
WARNER-LAMBERT COMPANY
Patent: EP237781 B1, 1991 ;
参考文献
Ramana, M. M. V.; Kudav, N. A.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1988 , vol. 27, # 1-12 p. 339 - 341
反应条件
1: ZnCl2/POCl3 / 3 h / Ambient temperature 2: 92 percent / 2percent aq. NaOH / 1 h / Ambient temperature View Scheme
参考文献
Heterocycles, , vol. 38, # 9 p. 2099 - 2114
