1: Methyltriphenylphosphonium bromide With n-butyllithium in tetrahydrofuran; hexane T=-15°C; 2: 4-fluoro-N-methoxy-N-methyl-benzamide in tetrahydrofuran; hexane T=-78 - 20°C; Wittig reaction; 3: With hydrogenchloride in tetrahydrofuran; diethyl ether; hexane T=20°C;
参考文献
Murphy, John A.; Commeureuc, Aurelien G. J.; Snaddon, Thomas N.; McGuire, Thomas M.; Khan, Tanweer A.; Hisler, Kevin; Dewis, Mark L.; Carling, Robert
Organic Letters, 2005 , vol. 7, # 7 p. 1427 - 1429
1: Methyltriphenylphosphonium bromide With n-butyllithium in tetrahydrofuran; hexane T=-15°C; 0.666667 h; 2: 4-fluoro-N-methoxy-N-methyl-benzamide in tetrahydrofuran; hexane T=-78 - 20°C; Wittig reaction; 20 h; 3: With sulfuric acid in tetrahydrofuran; hexane; water-d2 T=20°C; Title compound not separated from byproducts;
参考文献
Murphy, John A.; Commeureuc, Aurelien G. J.; Snaddon, Thomas N.; McGuire, Thomas M.; Khan, Tanweer A.; Hisler, Kevin; Dewis, Mark L.; Carling, Robert
Organic Letters, 2005 , vol. 7, # 7 p. 1427 - 1429
