甲氧甲酰基甲基三苯基溴化膦合成路线 （共 40 条）
反应条件
sodium ethanolate 1.) ethanol, 2.) ethanol, reflux 8 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Ganoub, Neven A. F.
Phosphorus, Sulfur and Silicon and the Related Elements, 1993 , vol. 81, # 1-4 p. 125 - 132
反应条件
n-butyllithium in tetrahydrofuran; hexane
0.5 h; Ambient temperature;
参考文献
McKenna, Eugene G.; Walker, Brian J.
Journal of the Chemical Society, Chemical Communications, 1989 , # 9 p. 568 - 569
反应条件
1: NaOCH3 / CH2Cl2 / Ambient temperature
2: H2 / 5percent Pd/C / methanol / 1 h / Ambient temperature
3: LiAlH4 / diethyl ether / 1 h / Heating
View Scheme
参考文献
Hashizume; Ito; Yamada; Nagashima; Kanao; Tomoda; Sunazuka; Kumagai; Omura
Chemical and pharmaceutical bulletin, 1994 , vol. 42, # 3 p. 512 - 520
反应条件
triethylamine in dichloromethane
0.166667 h; Ambient temperature;
参考文献
Lang, Robert W.; Hansen, Hans-Juergen
Helvetica Chimica Acta, 1980 , vol. 63, # 2 p. 438 - 455
反应条件
1: Br2 / H2O
2: KI / methanol
View Scheme
参考文献
Maerkl,G.
Chemische Berichte, 1961 , vol. 94, p. 2996 - 3004
反应条件
sodium acetate in acetonitrile
Condensation; Wittig reaction; 2 h; Heating;
参考文献
Hon, Yung-Son; Lee, Chia-Fu
Tetrahedron, 2000 , vol. 56, # 40 p. 7893 - 7902
反应条件
1: NaOCH3 / CH2Cl2 / Ambient temperature
2: H2 / Pt/C / methanol / 1 h / Ambient temperature
3: LiAlH4 / diethyl ether / 1 h / Heating
View Scheme
参考文献
Hashizume; Ito; Yamada; Nagashima; Kanao; Tomoda; Sunazuka; Kumagai; Omura
Chemical and pharmaceutical bulletin, 1994 , vol. 42, # 3 p. 512 - 520
反应条件
sodium methylate
1.) methanol, 10 min, 2.) methanol, RT, 1 h; Multistep reaction;
参考文献
Hashizume; Ito; Morikawa; Kanaya; Nagashima; Usui; Tomoda; Sunazuka; Kumagai; Omura
Chemical and Pharmaceutical Bulletin, 1994 , vol. 42, # 10 p. 2097 - 2107
反应条件
potassium carbonate; lithium bromide in tetrahydrofuran
6 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Zhu; Kayser
Synthetic Communications, 1994 , vol. 24, # 8 p. 1179 - 1186
反应条件
potassium tert-butylate in toluene
T=0°C;
参考文献
Fakhfakh, Mohammed A.; Fournet, Alain; Prina, Eric; Mouscadet, Jean-Francois; Franck, Xavier; Hocquemiller, Reynald; Figadere, Bruno
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 23 p. 5013 - 5023
