N-boc-4-氨基甲基苄氯合成路线 （共 4 条）
反应条件
tetrachloromethane; triphenylphosphine in dichloromethane T=20°C; Substitution; 24 h;
参考文献
Yu, Chongxi; Taylor, John W.
Bioorganic and Medicinal Chemistry, 1999 , vol. 7, # 1 p. 161 - 175
反应条件
1: lithium aluminum hydride / dioxane; tetrahydrofuran / Heating 2: 24.82 g / dioxane; H2O / 10 h / 20 °C 3: 75 percent / Ph3P; CCl4 / CH2Cl2 / 24 h / 20 °C View Scheme
参考文献
Yu, Chongxi; Taylor, John W.
Bioorganic and Medicinal Chemistry, 1999 , vol. 7, # 1 p. 161 - 175
反应条件
1: 24.82 g / dioxane; H2O / 10 h / 20 °C 2: 75 percent / Ph3P; CCl4 / CH2Cl2 / 24 h / 20 °C View Scheme
参考文献
Yu, Chongxi; Taylor, John W.
Bioorganic and Medicinal Chemistry, 1999 , vol. 7, # 1 p. 161 - 175
反应条件
1: 83.1 percent / H2O; ethanol / 5 h / Heating 2: conc. HCl / 4 h / Heating 3: 2.57 g / N,N-diisopropylethylamine / H2O; acetonitrile / 1.25 h View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 7, # 1 p. 161 - 175
