4-溴-2,3,5,6-四氟苯甲腈合成路线 （共 8 条）
反应条件
in further solvent(s) refluxing in N-methyl-2-pirrolydone 0.5 h; distn.;
参考文献
Gmelin Handbook: F: PerFHalOrg.9, 7, page 50 - 101
反应条件
1: With tin(ll) chloride; zinc in N,N-dimethyl-formamide Metallation; sonication; 2: With bromine in N,N-dimethyl-formamide Substitution; 1 h;
参考文献
Tetrahedron Letters, , vol. 41, # 20 p. 3817 - 3819
反应条件
sodium nitrite react with NaNO2 45 min, then in HF at 0°C, adding to soln. of CuBr in 48percent HBr at 0°C, 3 h;
参考文献
Gmelin Handbook: F: PerFHalOrg.9, 7, page 50 - 101
反应条件
1: FeCl3 / N,N-dimethyl-formamide 2: further solvent(s) View Scheme
参考文献
F: PerFHalOrg.9, 7, page 50 - 101
反应条件
1: FeCl3 / N,N-dimethyl-formamide 2: further solvent(s) View Scheme
参考文献
F: PerFHalOrg.9, 7, page 50 - 101
反应条件
1: pyridine / benzene 2: further solvent(s) View Scheme
参考文献
F: PerFHalOrg.9, 7, page 50 - 101
反应条件
2: further solvent(s) View Scheme
参考文献
F: PerFHalOrg.9, 7, page 50 - 101
反应条件
1: N,N-dimethyl-formamide 2: further solvent(s) View Scheme
参考文献
F: PerFHalOrg.9, 7, page 50 - 101
