3,3-双(甲硫基)-2-氰基丙烯酸乙酯合成路线 （共 33 条）
反应条件
1: 2 g / triethylamine / ethanol / 5 h / Heating 2: 80 percent / phosphoryl chloride, diethylaniline / 3 h / Heating View Scheme
参考文献
Ram, Vishnu J; Haque, Navedul; Nath, Mahendra
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1993 , vol. 32, # 7 p. 754 - 759
反应条件
potassium hydroxide in N,N-dimethyl-formamide
参考文献
Parmar, Virinder S.; Kumar, Ajay; Prasad, Ashok K.; Singh, Sanjay K.; Kumar, Naresh; Mukherjee, Shubhasish; Raj, Hanumantharao G.; Goel, Sanjay; Errington, William; Puar, Mohindar S.
Bioorganic and Medicinal Chemistry, 1999 , vol. 7, # 7 p. 1425 - 1436
反应条件
hydrazine monohydrochloride; sodium acetate in ethanol
T=90°C; 2 h;
参考文献
MITSUBISHI TANABE PHARMA CORPORATION
Patent: WO2008/4698 A2, 2008 ;
Location in patent: Page/Page column 126 ;
反应条件
in ethanol
24 h; Heating;
参考文献
El-Shafei, Ahmed Kamal; Soliman, Ahmed Mohamed; Sultan, Adel Abdel-Rahim; El-Saghier, Ahmed Mohamed Mohamed
Gazzetta Chimica Italiana, 1995 , vol. 125, # 3 p. 115 - 118
反应条件
potassium hydroxide in N,N-dimethyl-formamide
T=30°C; 6 h;
参考文献
Kumar, Ajay; Husain, Mofazzal; Prasad, Ashok K.; Singh, Ishwar; Vats, Archana; Sharma, Nawal K.; Sharma, Sunil K.; Gupta, Rajinder K.; Olsend, Carl E.; Bracke, Marc E.; Gross, Richard A.; Parmar, Virinder S.
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2003 , vol. 42, # 8 p. 1950 - 1957
反应条件
potassium hydroxide in N,N-dimethyl-formamide
6 h; Ambient temperature;
参考文献
Ram; Verma
Indian Journal of Chemistry - Section B Organic Chemistry Including Medicinal Chemistry, 1990 , vol. 29, # 7 p. 624 - 627
反应条件
potassium hydroxide in N,N-dimethyl-formamide
参考文献
Parmar, Virinder S.; Kumar, Ajay; Prasad, Ashok K.; Singh, Sanjay K.; Kumar, Naresh; Mukherjee, Shubhasish; Raj, Hanumantharao G.; Goel, Sanjay; Errington, William; Puar, Mohindar S.
Bioorganic and Medicinal Chemistry, 1999 , vol. 7, # 7 p. 1425 - 1436
反应条件
Ambient temperature;
参考文献
Ram, Vishnu J.; Haque, Navedul; Nath, Mahendra; Singh, Sunil K.; Hussaini, Falak A.; Tripathi; Shoeb
Bioorganic and Medicinal Chemistry Letters, 1997 , vol. 7, # 24 p. 3149 - 3152
反应条件
potassium hydroxide in N,N-dimethyl-formamide
参考文献
Ram, Vishnu J.; Haque, Navedul; Nath, Mahendra; Singh, Sunil K.; Hussaini, Falak A.; Tripathi; Shoeb
Bioorganic and Medicinal Chemistry Letters, 1997 , vol. 7, # 24 p. 3149 - 3152
反应条件
1: 88 percent / ethanol / 10 h / Heating
2: 80 percent / 85percent NH2-NH2*H2O / ethanol / Heating
View Scheme
参考文献
Schulz, Manfred; Moegel, Liena; Riediger, Werner; Nghiem-Xuan-Dung; Radeglia, Reiner
Journal fuer Praktische Chemie (Leipzig), 1982 , vol. 324, # 2 p. 309 - 321
