1,4-piperazinebis(ethane sulfonic acid) 1.5-Na salt in 1,4-dioxane; water 264 h; Heating;

NADP+; dianionic G6P in aq. phosphate buffer; dimethyl sulfoxide T=37°C; pH=7.4; 1 h; Enzymatic reaction;

1: 74 percent / H2SO4 / 0.42 h / Heating 2: thionyl chloride / diethyl ether; benzene 3: 50 percent aq. NaOH / 1,2-dimethoxy-ethane; H2O 4: 57 percent / 1,4-piperazinebis(ethane sulfonic acid) 1.5-Na salt / dioxane; H2O / 264 h / Heating View Scheme

1: thionyl chloride / diethyl ether; benzene 2: 50 percent aq. NaOH / 1,2-dimethoxy-ethane; H2O 3: 57 percent / 1,4-piperazinebis(ethane sulfonic acid) 1.5-Na salt / dioxane; H2O / 264 h / Heating View Scheme

1: 50 percent aq. NaOH / 1,2-dimethoxy-ethane; H2O 2: 57 percent / 1,4-piperazinebis(ethane sulfonic acid) 1.5-Na salt / dioxane; H2O / 264 h / Heating View Scheme