Alpha-甲酰基苯乙酸乙酯合成路线 （共 38 条）
反应条件
Erhitzen des oeligen Reaktionsprodukts (β-Anilino-α-phenyl-acrylsaeureaethylester?) auf 260 gradC;
参考文献
Boerner
Dissertation <Wuerzburg 1899>, S. 38; C. 1900, I, 122
反应条件
1: ammonium chloride; alcohol 2: alcoholic NaOH-solution 3: 145 °C View Scheme
参考文献
Wislicenus; Bilhuber
Chemische Berichte, 1918 , vol. 51, p. 1370
反应条件
4-toluenesulfonyl azide; triethylamine in dichloromethane
参考文献
Regitz,M.; Menz,F.
Chemische Berichte, 1968 , vol. 101, # 8 p. 2622 - 2632
反应条件
1: pyridine
2: methanol; aq. NaOH solution
View Scheme
参考文献
Borsche; Niemann
Chemische Berichte, 1936 , vol. 69, p. 1993,1996
反应条件
(i) NaOEt, EtOH, (ii) /BRN= 640188/, AcOH; Multistep reaction;
参考文献
Falch,E.; Natvig,T.
Acta Chemica Scandinavica (1947-1973), 1970 , vol. 24, # 4 p. 1423 - 1430
参考文献
de Sarlo,F. et al.
Tetrahedron, 1966 , vol. 22, p. 2989 - 2994
反应条件
1: 73 percent / piperidine / acetic acid / 16 h / Heating
2: 55 percent / conc. hydrochloric acid / 5 h / Heating
3: 88 percent / copper powder / quinoline / 1 h / 200 - 210 °C
View Scheme
参考文献
Lyukmanov, N. F.; Kovshev, E. I.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1985 , vol. 21, # 11 p. 1215 - 1218
Khimiya Geterotsiklicheskikh Soedinenii, 1985 , vol. 21, # 11 p. 1477 - 1480
反应条件
potassium tert-butylate; acetyl chloride
1) acetone, tert.-butyl alcohol, 1.5 h, reflux, 2) 4 h, reflux; Yield given. Multistep reaction;
参考文献
Lyukmanov, N. F.; Kovshev, E. I.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1985 , vol. 21, # 11 p. 1215 - 1218
Khimiya Geterotsiklicheskikh Soedinenii, 1985 , vol. 21, # 11 p. 1477 - 1480
反应条件
1: NaOAc / H2O; ethanol
2: SOCl2 / 0 - 60 °C
View Scheme
参考文献
Tripathy, Rabindranath; Ghose, Arup; Singh, Jasbir; Bacon, Edward R.; Angeles, Thelma S.; Yang, Shi X.; Albom, Mark S.; Aimone, Lisa D.; Herman, Joseph L.; Mallamo, John P.
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 6 p. 1793 - 1798
反应条件
1: urea; aq. NaOH solution
2: POCl3
View Scheme
参考文献
Davies; Piggott
Journal of the Chemical Society, 1945 , p. 347 Anm.
