(2S,3s)-n-3-羟基吡咯烷-苯基甘氨酰胺合成路线 （共 2 条）
反应条件
1.1: sodium hydrogencarbonate / 18 h / 20 - 35 °C 2.1: dicyclohexyl-carbodiimide; benzotriazol-1-ol / dichloromethane / 0.17 h / 20 - 35 °C 2.2: 12 h / 20 - 35 °C 3.1: hydrogen; palladium 10 on activated carbon / methanol / 2 h / 20 °C View Scheme
参考文献
DR. REDDY'S LABORATORIES LTD.; DR. REDDY'S LABORATORIES, INC.; SASMAL, Pradip Kumar; CHINTAKUNTA, Vamsee Krishna; POTLURI, Vijay; KHANNA, Ish Kumar; TEHIM, Ashok; JALEEL, Mahaboobi; HOGBERG, Thomas; RIST, Oystein; ELSTER, Lisbeth; FRIMURER, Thomas Michael; GERLACH, Lars-Ole
Patent: WO2012/12410 A2, 2012 ;
WO 2012/012410 A2
反应条件
1.1: dicyclohexyl-carbodiimide; benzotriazol-1-ol / dichloromethane / 0.17 h / 20 - 35 °C 1.2: 12 h / 20 - 35 °C 2.1: hydrogen; palladium 10 on activated carbon / methanol / 2 h / 20 °C View Scheme
参考文献
DR. REDDY'S LABORATORIES LTD.; DR. REDDY'S LABORATORIES, INC.; SASMAL, Pradip Kumar; CHINTAKUNTA, Vamsee Krishna; POTLURI, Vijay; KHANNA, Ish Kumar; TEHIM, Ashok; JALEEL, Mahaboobi; HOGBERG, Thomas; RIST, Oystein; ELSTER, Lisbeth; FRIMURER, Thomas Michael; GERLACH, Lars-Ole
Patent: WO2012/12410 A2, 2012 ;
WO 2012/012410 A2
