1: (2-chlorophenyl)methanol With [2,2']bipyridinyl; copper(l) chloride in N,N-dimethyl-formamide T=20°C; 24 h; 2: acetone With Tris-HCl in water; N,N-dimethyl-formamide T=0°C; direct asymmetric aldol reaction; pH=7.8; 24 h; optical yield given as percent ee;
参考文献
Akagawa, Kengo; Takigawa, Shota; Mano, Erika; Kudo, Kazuaki
Tetrahedron Letters, 2011 , vol. 52, # 7 p. 770 - 773