caesium carbonate; tetrakis(triphenylphosphine) palladium(0) in 1,4-dioxane Suzuki coupling reaction; 4 h; Heating;

1: 71 percent / 10 h / 90 °C 2: 63 percent / acetic acid / 2 h / Heating 3: 100 percent / K2CO3; water / methanol / 3 h / 20 °C 4: 84 percent / POCl3 / 0.5 h / 90 °C 5: 91 percent / cesium carbonate / Pd(PPh3)4 / dioxane / 4 h / Heating View Scheme

1: 63 percent / acetic acid / 2 h / Heating 2: 100 percent / K2CO3; water / methanol / 3 h / 20 °C 3: 84 percent / POCl3 / 0.5 h / 90 °C 4: 91 percent / cesium carbonate / Pd(PPh3)4 / dioxane / 4 h / Heating View Scheme

1: 84 percent / POCl3 / 0.5 h / 90 °C 2: 91 percent / cesium carbonate / Pd(PPh3)4 / dioxane / 4 h / Heating View Scheme

1: 100 percent / K2CO3; water / methanol / 3 h / 20 °C 2: 84 percent / POCl3 / 0.5 h / 90 °C 3: 91 percent / cesium carbonate / Pd(PPh3)4 / dioxane / 4 h / Heating View Scheme

1: 71 percent / 10 h / 90 °C 2: 63 percent / acetic acid / 2 h / Heating 3: 100 percent / K2CO3; water / methanol / 3 h / 20 °C 4: 84 percent / POCl3 / 0.5 h / 90 °C 5: 91 percent / cesium carbonate / Pd(PPh3)4 / dioxane / 4 h / Heating View Scheme