(S)-氮丙啶-1,2-二羧酸二叔丁酯合成路线 （共 11 条）
反应条件
in tetrahydrofuran T=-78 - -20°C; Inert atmosphere;
参考文献
Wu, Yan-Chao; Zhu, Jieping
Organic Letters, 2009 , vol. 11, # 23 p. 5558 - 5561
反应条件
boron trifluoride diethyl etherate in cyclohexane; acetone 12 h;
参考文献
Baldwin, Jack E.; Farthing, Christopher N.; Russell, Andrew T.; Schofield, Christopher J.; Spivey, Alan C.
Tetrahedron Letters, 1996 , vol. 37, # 21 p. 3761 - 3764
反应条件
1: H2 / 10percent Pd/C / 4 h / 20 °C / 760 Torr 2: 1.) diethoxytriphenylphosphorane; 2.) DMAP / 1.) toluene, 20-40 degC, 24 h; 2.) MeCN View Scheme
参考文献
Baldwin, Jack E.; Farthing, Christopher N.; Russell, Andrew T.; Schofield, Christopher J.; Spivey, Alan C.
Tetrahedron Letters, 1996 , vol. 37, # 21 p. 3761 - 3764
反应条件
1: 96 percent / LiOH / H2O; dioxane 2: 19 percent / BF3*Et2O / acetone; cyclohexane / 12 h View Scheme
参考文献
Baldwin, Jack E.; Farthing, Christopher N.; Russell, Andrew T.; Schofield, Christopher J.; Spivey, Alan C.
Tetrahedron Letters, 1996 , vol. 37, # 21 p. 3761 - 3764
反应条件
4-(N,N-dimethlyamino)pyridine; Diethyloxytriphenylphosphorane 1.) toluene, 20-40 degC, 24 h; 2.) MeCN; Yield given. Multistep reaction;
参考文献
Baldwin, Jack E.; Farthing, Christopher N.; Russell, Andrew T.; Schofield, Christopher J.; Spivey, Alan C.
Tetrahedron Letters, 1996 , vol. 37, # 21 p. 3761 - 3764
反应条件
4-(N,N-dimethlyamino)pyridine; Diethyloxytriphenylphosphorane 1.) toluene, 20-40 degC, 24 h; 2.) MeCN; Multistep reaction;
参考文献
Baldwin, Jack E.; Farthing, Christopher N.; Russell, Andrew T.; Schofield, Christopher J.; Spivey, Alan C.
Tetrahedron Letters, 1996 , vol. 37, # 21 p. 3761 - 3764
反应条件
1: 50 percent / CuBr*Me2S / tetrahydrofuran / 4 h / -40 °C 2: trifluoroacetic acid View Scheme
参考文献
Baldwin, Jack E.; Farthing, Christopher N.; Russell, Andrew T.; Schofield, Christopher J.; Spivey, Alan C.
Tetrahedron Letters, 1996 , vol. 37, # 21 p. 3761 - 3764
反应条件
1: 50 percent / CuBr*Me2S / toluene / 4 h / -50 °C 2: trifluoroacetic acid View Scheme
参考文献
Baldwin, Jack E.; Farthing, Christopher N.; Russell, Andrew T.; Schofield, Christopher J.; Spivey, Alan C.
Tetrahedron Letters, 1996 , vol. 37, # 21 p. 3761 - 3764
反应条件
1: 71 percent / CuBr*Me2S / toluene / 4 h / -40 °C 2: trifluoroacetic acid View Scheme
参考文献
Baldwin, Jack E.; Farthing, Christopher N.; Russell, Andrew T.; Schofield, Christopher J.; Spivey, Alan C.
Tetrahedron Letters, 1996 , vol. 37, # 21 p. 3761 - 3764
反应条件
1: 83 percent / CuBr*Me2S / toluene / 1 h / -20 °C 2: trifluoroacetic acid View Scheme
参考文献
Baldwin, Jack E.; Farthing, Christopher N.; Russell, Andrew T.; Schofield, Christopher J.; Spivey, Alan C.
Tetrahedron Letters, 1996 , vol. 37, # 21 p. 3761 - 3764
