(S)-N-[2-(2,3-二氢-6-甲氧基-1H-茚-1-基)乙基]丙酰胺合成路线 （共 29 条）
反应条件
1: Et3N / tetrahydrofuran / 0 °C 2: H2 / Ru(OCOCH3)2[(S)-BINAP] / methanol / 70 °C / 68255.5 Torr View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 45, # 19 p. 4212 - 4221
反应条件
sodium hydroxide in tetrahydrofuran T=0°C; Schotten-Baumann acylation;
参考文献
Journal of Medicinal Chemistry, , vol. 45, # 19 p. 4212 - 4221
反应条件
1: N2H4*H2O / Heating 2: 1 M aq. NaOH / tetrahydrofuran / 0 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 45, # 19 p. 4212 - 4221
反应条件
Corynebacterium ammoniagenes IFO12612 in methanol T=37°C; 24 h;
参考文献
Bioscience, Biotechnology and Biochemistry, , vol. 66, # 2 p. 464 - 466
反应条件
1: triethylamine / dichloromethane 2: N,N-dimethyl-formamide 3: hydrazine / ethanol 4: sodium hydroxide / tetrahydrofuran; water View Scheme
参考文献
Chinese Chemical Letters, , vol. 22, # 3 p. 264 - 267
反应条件
1: hydrazine / ethanol 2: sodium hydroxide / tetrahydrofuran; water View Scheme
参考文献
Chinese Chemical Letters, , vol. 22, # 3 p. 264 - 267
反应条件
1: lithium aluminium tetrahydride / tetrahydrofuran 2: triethylamine / dichloromethane 3: sodium periodate; potassium permanganate / water; acetone 4: oxalyl dichloride / dichloromethane; N,N-dimethyl-formamide 5: tin(IV) chloride / dichloromethane 6: 10 palladium on activated charcoal; sulfuric acid; hydrogen / ethanol 7: triethylamine / dichloromethane 8: N,N-dimethyl-formamide 9: hydrazine / ethanol 10: sodium hydroxide / tetrahydrofuran; water View Scheme
参考文献
Chinese Chemical Letters, , vol. 22, # 3 p. 264 - 267
反应条件
1: triethylamine / dichloromethane 2: sodium periodate; potassium permanganate / water; acetone 3: oxalyl dichloride / dichloromethane; N,N-dimethyl-formamide 4: tin(IV) chloride / dichloromethane 5: 10 palladium on activated charcoal; sulfuric acid; hydrogen / ethanol 6: triethylamine / dichloromethane 7: N,N-dimethyl-formamide 8: hydrazine / ethanol 9: sodium hydroxide / tetrahydrofuran; water View Scheme
参考文献
Chinese Chemical Letters, , vol. 22, # 3 p. 264 - 267
反应条件
1: sodium periodate; potassium permanganate / water; acetone 2: oxalyl dichloride / dichloromethane; N,N-dimethyl-formamide 3: tin(IV) chloride / dichloromethane 4: 10 palladium on activated charcoal; sulfuric acid; hydrogen / ethanol 5: triethylamine / dichloromethane 6: N,N-dimethyl-formamide 7: hydrazine / ethanol 8: sodium hydroxide / tetrahydrofuran; water View Scheme
参考文献
Chinese Chemical Letters, , vol. 22, # 3 p. 264 - 267
反应条件
1: oxalyl dichloride / dichloromethane; N,N-dimethyl-formamide 2: tin(IV) chloride / dichloromethane 3: 10 palladium on activated charcoal; sulfuric acid; hydrogen / ethanol 4: triethylamine / dichloromethane 5: N,N-dimethyl-formamide 6: hydrazine / ethanol 7: sodium hydroxide / tetrahydrofuran; water View Scheme
参考文献
Chinese Chemical Letters, , vol. 22, # 3 p. 264 - 267
