3-(叔丁基硫代)吡啶-2-羧酸合成路线 （共 3 条）
反应条件
1: With water; sodium hydroxide in ethanol 1 h; Inert atmosphereReflux; 2: pH=2; Acidic aqueous solution; Product distribution / selectivity;
参考文献
ACHAOGEN, INC.; WAGMAN, Allan, Scott; MOSER, Heinz, Ernst
Patent: WO2010/30811 A2, 2010 ;
Location in patent: Page/Page column 77 ;
WO 2010/030811 A2
反应条件
1: 5.4 g / NaH / tetrahydrofuran / 1.5 h / Heating 2: 85 percent / NaOH / ethanol; H2O / 1 h / Heating View Scheme
参考文献
Tetrahedron Letters, , vol. 37, # 21 p. 3617 - 3618
反应条件
1: 91 percent / 2.00 N HCl / 11 h / Heating 2: 74 percent / 2.50 N NaOH / 1 h View Scheme
参考文献
Cai, Zhenhong R.; Jabri, Salman Y.; Jin, Haolun; Lansdown, Rachael A.; Metobo, Samuel E.; Mish, Michael R.; Pastor, Richard M.
Patent: US2008/58315 A1, 2008 ;
Location in patent: Page/Page column 38-39 ;
