1: HCl / 0.25 h / Ambient temperature 2: 97 percent / Et3N, Ag2O / CHCl3 / 24 h / Ambient temperature 3: 95 percent / aq. HNO3 / 0.03 h / Ambient temperature View Scheme

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1210429', constants.ctx, '0')">sodium dithionite</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1696894', constants.ctx, '0')">diethyl ether</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '1731042', constants.ctx, '0')">chloroform</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '3587155', constants.ctx, '0')">water</a> <br />&nbsp;Yield given;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 4 steps<br /> </b>1: 91 percent / NaOAc, H₂ / Pd/C (10 percent Pd) / methanol / 10 h / 40 - 45 &deg;C / Irradiation<br />2: 73 percent / 1) 2 N NaOH, 2) FeCl₃*6H₂O/HCl / 1) MeOH, reflux, 2) H₂O<br />3: 98 percent / Ag₂O / CHCl₃ / Heating<br />4: Na₂S₂O₄ / diethyl ether; CHCl₃; H₂O<br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: AcOH / CH₂Cl₂ / Ambient temperature<br />2: Na₂S₂O₄ / ethyl acetate<br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: 2.) AcOH / 1.) CH₂Cl₂ <br />2: aq. Na₂S₂O₄ / ethyl acetate<br /> <br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1: 73 percent / 1) 2 N NaOH, 2) FeCl₃*6H₂O/HCl / 1) MeOH, reflux, 2) H₂O<br />2: 98 percent / Ag₂O / CHCl₃ / Heating<br />3: Na₂S₂O₄ / diethyl ether; CHCl₃; H₂O<br /> <br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1: CH₂Cl₂ / 18 h / Ambient temperature<br />2: AcOH / CH₂Cl₂ / Ambient temperature<br />3: Na₂S₂O₄ / ethyl acetate<br /> <br /> &nbsp;

<b>Multi-step reaction with 6 steps<br /> </b>1: 1) AlCl₃, NaCl, 2) conc. HCl, H₂O / 1) melt, 180 deg C, 2) 0 deg C, 3 h<br />2: 90 percent / Zn / pyridine<br />3: 91 percent / NaOAc, H₂ / Pd/C (10 percent Pd) / methanol / 10 h / 40 - 45 &deg;C / Irradiation<br />4: 73 percent / 1) 2 N NaOH, 2) FeCl₃*6H₂O/HCl / 1) MeOH, reflux, 2) H₂O<br />5: 98 percent / Ag₂O / CHCl₃ / Heating<br />6: Na₂S₂O₄ / diethyl ether; CHCl₃; H₂O<br /> <br /> &nbsp;