N-[(1,1-二甲基乙氧基)羰基]-L-异亮氨酸甲酯合成路线 （共 18 条）
反应条件
1: 79 percent / DCC; HOBt / dimethylformamide 2: 56 percent / DMAP / acetonitrile 3: 72 percent / acetonitrile / 20 °C View Scheme
参考文献
Sameiro, M; Goncalves, T; Maia, Hernani L.S
Tetrahedron Letters, 2001 , vol. 42, # 44 p. 7775 - 7777
反应条件
1: 1.) H2, 2.) PPTS, 3.) PDC / 1.) PtO2 / 1.) MeOH, 2.) EtOH, reflux, 3.) DMF 2: 95 percent View Scheme
参考文献
D'Aniello, Fabiana; Mann, Andre; Taddei, Maurizio; Wermuth, Camille-Georges
Tetrahedron Letters, 1994 , vol. 35, # 42 p. 7775 - 7778
参考文献
D'Aniello, Fabiana; Mann, Andre; Taddei, Maurizio; Wermuth, Camille-Georges
Tetrahedron Letters, 1994 , vol. 35, # 42 p. 7775 - 7778
反应条件
1: thionyl chloride / 18.5 h / 0 - 25 °C 2: triethylamine / dichloromethane / 24 h / 25 °C View Scheme
参考文献
Yang, Dezhi; Wang, Peng; Liu, Jianzhen; Xing, Hualu; Liu, Yang; Xie, Wencheng; Zhao, Guisen
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 1 p. 366 - 373
反应条件
lithium borohydride in ethylene glycol dimethyl ether
参考文献
Van den Broek; Fennis; Arevalo; Lazaro; Ballesta; Lelieveld; Ottenheijm
European Journal of Medicinal Chemistry, 1989 , vol. 24, # 5 p. 503 - 510
反应条件
lithium borohydride in ethylene glycol dimethyl ether
参考文献
Van den Broek; Fennis; Arevalo; Lazaro; Ballesta; Lelieveld; Ottenheijm
European Journal of Medicinal Chemistry, 1989 , vol. 24, # 5 p. 503 - 510
反应条件
trifluoroacetic acid T=20°C; Hydrolysis; 4 h;
参考文献
Lin; Chen; You; Chen Liu; Lee
Journal of Natural Products, 2000 , vol. 63, # 10 p. 1338 - 1343
反应条件
hydrogenchloride in ethyl acetate T=20°C; 5 h;
参考文献
Gallardo, Gabriela L.; Butler, Matias; Gallo, Mariana L.; Rodriguez, M. Alejandra; Eberlin, Marcos N.; Cabrera, Gabriela M.
Phytochemistry, 2006 , vol. 67, # 21 p. 2403 - 2410
