1: With diethylamine T=53°C; 12 h; 2: in acetic acid T=40°C; 1 h;

1.1: BH3*THF / tetrahydrofuran / 2 h / 20 °C 1.2: 85 percent / BuLi / tetrahydrofuran / -78 - 20 °C 2.1: Et2NH / 12 h / 53 °C 2.2: 60 percent / acetic acid / 1 h / 40 °C View Scheme