4-(1-甲基-1H-吡唑-5-基)苯甲醛合成路线 （共 6 条）
反应条件
PdCl(C3H5)(dppb); potassium acetate in N,N-dimethyl-formamide T=150°C; 72 h; Inert atmosphere; Reagent/catalyst; Overall yield = 38 percent;
参考文献
Tetrahedron Letters, , vol. 55, # 10 p. 1697 - 1701
反应条件
manganese(IV) oxide in acetone 1 h; Heating;
参考文献
Tanaka, Akira; Terasawa, Takeshi; Hagihara, Hiroyuki; Sakuma, Yuri; Ishibe, Noriko; Sawada, Masae; Takasugi, Hisashi; Tanaka, Hirokazu
Journal of Medicinal Chemistry, 1998 , vol. 41, # 13 p. 2390 - 2410
反应条件
potassium acetate; palladium diacetate in N,N-dimethyl acetamide T=150°C; 20 h; Inert atmosphere; regioselective reaction;
参考文献
Beladhria, Anissa; Beydoun, Kassem; Ammar, Hamed Ben; Salem, Ridha Ben; Doucet, Henri
Synthesis, 2011 , # 16 art. no. C22411SS, p. 2553 - 2560
反应条件
1: 86 percent / 18 h / 85 °C 2: 34 percent / AcOH / 3 h / Ambient temperature 3: 99 percent / LiAlH4 / tetrahydrofuran / 0.5 h / 5 °C 4: 93 percent / MnO2 / acetone / 1 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 41, # 13 p. 2390 - 2410
反应条件
1: 34 percent / AcOH / 3 h / Ambient temperature 2: 99 percent / LiAlH4 / tetrahydrofuran / 0.5 h / 5 °C 3: 93 percent / MnO2 / acetone / 1 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 41, # 13 p. 2390 - 2410
反应条件
1: 99 percent / LiAlH4 / tetrahydrofuran / 0.5 h / 5 °C 2: 93 percent / MnO2 / acetone / 1 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 41, # 13 p. 2390 - 2410
