3-(1-甲基-1H-吡唑-5-基)苯甲腈合成路线 （共 5 条）
反应条件
PdCl(C3H5)(dppb); potassium acetate in N,N-dimethyl-formamide T=150°C; 72 h; Inert atmosphere; Overall yield = 44 percent;
参考文献
Takfaoui, Abdelilah; Zhao, Liqin; Touzani, Rachid; Dixneuf, Pierre H.; Doucet, Henri
Tetrahedron Letters, 2014 , vol. 55, # 10 p. 1697 - 1701
反应条件
potassium acetate; palladium diacetate in N,N-dimethyl acetamide T=150°C; 20 h; Inert atmosphere; regioselective reaction;
参考文献
Beladhria, Anissa; Beydoun, Kassem; Ammar, Hamed Ben; Salem, Ridha Ben; Doucet, Henri
Synthesis, 2011 , # 16 art. no. C22411SS, p. 2553 - 2560
反应条件
acetic acid 3.5 h; Ambient temperature;
参考文献
Tanaka, Akira; Terasawa, Takeshi; Hagihara, Hiroyuki; Sakuma, Yuri; Ishibe, Noriko; Sawada, Masae; Takasugi, Hisashi; Tanaka, Hirokazu
Journal of Medicinal Chemistry, 1998 , vol. 41, # 13 p. 2390 - 2410
反应条件
1: 79 percent / 2 h / 90 °C 2: 29 percent / AcOH / 3.5 h / Ambient temperature View Scheme
参考文献
Tanaka, Akira; Terasawa, Takeshi; Hagihara, Hiroyuki; Sakuma, Yuri; Ishibe, Noriko; Sawada, Masae; Takasugi, Hisashi; Tanaka, Hirokazu
Journal of Medicinal Chemistry, 1998 , vol. 41, # 13 p. 2390 - 2410
反应条件
diisobutylaluminium hydride in dichloromethane; toluene T=-60°C; 0.5 h;
参考文献
Tanaka, Akira; Terasawa, Takeshi; Hagihara, Hiroyuki; Sakuma, Yuri; Ishibe, Noriko; Sawada, Masae; Takasugi, Hisashi; Tanaka, Hirokazu
Journal of Medicinal Chemistry, 1998 , vol. 41, # 13 p. 2390 - 2410
