[4-(5-噁唑基)苯基]甲醇合成路线 （共 3 条）
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=5°C; 0.5 h;
参考文献
Tanaka, Akira; Terasawa, Takeshi; Hagihara, Hiroyuki; Sakuma, Yuri; Ishibe, Noriko; Sawada, Masae; Takasugi, Hisashi; Tanaka, Hirokazu
Journal of Medicinal Chemistry, 1998 , vol. 41, # 13 p. 2390 - 2410
反应条件
1: 82 percent / K2CO3 / methanol / 3.5 h / Heating 2: 87 percent / LiAlH4 / tetrahydrofuran / 0.5 h / 5 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 41, # 13 p. 2390 - 2410
反应条件
oxalyl dichloride; dimethyl sulfoxide; triethylamine 1.) CH2Cl2, -60 deg C, 1 h, 2.) CH2Cl2, from -60 deg C to RT, 1 h; Yield given. Multistep reaction;
参考文献
Fujifilm RI Pharma Co., Ltd.; Daiichi Sankyo Company, Limited
Patent: EP1956013 A1, 2008 ;
Location in patent: Page/Page column 26 ;
