6-甲基-2,4-嘧啶二胺合成路线 (共 12 条)
参考文献
Chemische Berichte, , vol. 34, p. 1242
反应条件
potassium hydroxide in water
反应条件
zinc(II) chloride in isopropyl alcohol; toluene T=90°C; 16 h; Inert atmosphere;
参考文献
Letinois, Ulla; Schuetz, Jan; Haerter, Ralph; Stoll, Rinke; Huffschmidt, Florian; Bonrath, Werner; Karge, Reinhard
Organic Process Research and Development, 2013 , vol. 17, # 3 p. 427 - 431
参考文献
Chemische Berichte, , vol. 34, p. 1242
反应条件
sodium amide; decalin
参考文献
Yakugaku Zasshi, , vol. 59, p. 18,26; dtsch. Ref. S. 97, 103, 104
Chem.Abstr., , p. 3791
反应条件
sodium 1.) MeOH, 20 deg C, 20 min, 2.) 2-methoxyethanol, reflux, 6 h; Yield given. Multistep reaction;
参考文献
Australian Journal of Chemistry, , vol. 37, # 6 p. 1195 - 1201
参考文献
Chemische Berichte, , vol. 32, p. 2934
Chemische Berichte, , vol. 35, p. 1570
参考文献
Chemische Berichte, , vol. 34, p. 1242
反应条件
iodine cloride in methanol T=25°C; 14 h;
参考文献
Pelphrey, Phillip M.; Popov, Veljko M.; Joska, Tammy M.; Beierlein, Jennifer M.; Bolstad, Erin S. D.; Fillingham, Yale A.; Wright, Dennis L.; Anderson, Amy C.
Journal of Medicinal Chemistry, 2007 , vol. 50, # 5 p. 940 - 950
反应条件
sulfuric acid; nitric acid T=70°C;
参考文献
Gabriel; Colman
Chemische Berichte, 1901 , vol. 34, p. 1242