反应条件
1: 1-(benzyloxy)-4-iodo-1H-pyrazole; (Z)-2,2'-(1-phenylbut-1-ene-1,2-diyl)bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane) With potassium hydroxide; 3,5-dimethoxy-phenol; tetrakis(triphenylphosphine) palladium(0) in ethylene glycol dimethyl ether
T=20°C; Suzuki coupling reaction; 24 h;
2: iodobenzene With potassium hydroxide; 3,5-dimethoxy-phenol; tetrakis(triphenylphosphine) palladium(0) in ethylene glycol dimethyl ether
T=20°C; Suzuki coupling reaction; 24 h;
参考文献
Wenckens, Martin; Jakobsen, Palle; Vedso, Per; Huusfeldt, Per Olaf; Gissel, Birgitte; Barfoed, Marianne; Brockdorff, Bettina Lundin; Lykkesfeldt, Anne E.; Begtrup, Mikael
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 8 p. 1883 - 1899