(4E)-5-苯基-4-戊烯酸合成路线 （共 6 条）
参考文献
Uchida, Itsuo; Itoh, Yoshikuni; Namiki, Takayuki; Nishikawa, Motoaki; Hashimoto, Masashi
Tetrahedron Letters, 1986 , vol. 27, # 18 p. 2015 - 2018
参考文献
Fichter; Bauer
Chemische Berichte, 1898 , vol. 31, p. 2001
反应条件
1: diethyl ether; methanol 2: DIBAL-H / CH2Cl2 / 0.5 h / 0 °C 3: H2 / PtO2 / methanol / 2585.7 Torr View Scheme
参考文献
Gribble, Andrew D.; Dolle, Roland E.; Shaw, Antony; McNair, David; Novelli, Riccardo; Novelli, Christine E.; Slingsby, Brian P.; Shah, Virendra P.; Tew, David; Saxty, Barbara A.; Allen, Mark; Groot, Pieter H.; Pearce, Nigel; Yates, John
Journal of Medicinal Chemistry, 1996 , vol. 39, # 18 p. 3569 - 3584
反应条件
1: 1.) 10percent NaOH, 2.) (COCl)2
2: benzene
3: 74 percent / LiAlH4 / tetrahydrofuran / 1.) 60 deg C, 1.5 h, 2.) room temperature, overnight
4: 1.) BuLi / 1.) THF, - 78 deg C, 30 min., 2.) - 10 deg C, 30 min, 3.) HMPA, lithium perchlorate, electrolysis, 10 mA/cm2, -10 deg C
View Scheme
参考文献
Tokuda; Miyamoto; Fujita; Suginome
Tetrahedron, 1991 , vol. 47, # 4-5 p. 747 - 756
参考文献
Erlenmeyer jun; Kreutz
Chemische Berichte, 1905 , vol. 38, p. 3505
Full Text Show Details
Riiber
Chemische Berichte, 1905 , vol. 38, p. 2743
参考文献
Erlenmeyer jun; Kreutz
Chemische Berichte, 1905 , vol. 38, p. 3505
Full Text Show Details
Riiber
Chemische Berichte, 1905 , vol. 38, p. 2743
