2-氟-4-溴苯甲酸甲酯合成路线 （共 12 条）
反应条件
bis-triphenylphosphine-palladium(II) chloride; carbon monoxide in N,N-dimethyl-formamide
T=110°C; 2 h;
参考文献
Zimmerman, Sommer S.; Khatri, Alpa; Garnier-Amblard, Ethel C.; Mullasseril, Praseeda; Kurtkaya, Natalie L.; Gyoneva, Stefka; Hansen, Kasper B.; Traynelis, Stephen F.; Liotta, Dennis C.
Journal of Medicinal Chemistry, 2014 , vol. 57, # 6 p. 2334 - 2356
反应条件
potassium acetate; bis-triphenylphosphine-palladium(II) chloride in 1,4-dioxane
T=100°C;
参考文献
ELI LILLY AND COMPANY
Patent: WO2004/94382 A1, 2004 ;
Location in patent: Page 20 ;
WO 2004/094382 A1
