2-(甲氧基羰基)苯基异氰酸酯合成路线 （共 17 条）
反应条件
1: 2-bromophenyl isocyanide With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 0.25 h; Inert atmosphere; 2: 2-methoxycarbonylphenyl isocyanate in tetrahydrofuran; hexane T=-78 - 20°C; Inert atmosphere;
参考文献
Organic Letters, , vol. 11, # 2 p. 389 - 392
参考文献
Peet,N.P.; Sunder,S.
Journal of Organic Chemistry, 1974 , vol. 39, p. 1931 - 1935
反应条件
N-ethyl-N,N-diisopropylamine in tetrahydrofuran 24 h; Ambient temperature;
参考文献
Hays, Sheryl J.; Caprathe, Bradley W.; Gilmore, John L.; Amin, Nilam; Emmerling, Mark R.; Michael, Walter; Nadimpalli, Ravi; Nath, Rathna; Raser, Kadee J.; Stafford, Daniel; Watson, Desiree; Wang, Kevin; Jaen, Juan C.
Journal of Medicinal Chemistry, 1998 , vol. 41, # 7 p. 1060 - 1067
反应条件
1: 81 percent / H2O; tetrahydrofuran
2: 88 percent / 2 h / Heating
View Scheme
参考文献
Peet
Journal of Heterocyclic Chemistry, 1987 , vol. 24, # 1 p. 223 - 225
反应条件
2: 58 percent / toluene
View Scheme
参考文献
Kornet; Varia; Beaven
Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 5 p. 1533 - 1535
反应条件
1: 96 percent / tetrahydrofuran / 1) 0 deg C, 30 min; 2) room temp., 3 h
2: 93 percent / various solvent(s) / 2 h / 150 - 160 °C
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参考文献
Chau, Nguyen; Saegusa, Yasuo; Iwakura, Yoshio
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 541 - 544
反应条件
1: 82 percent / triethylamine / toluene / 4 h / Heating
2: 60 percent / ethanol / Heating
3: 60 percent / conc. HCl / ethanol / 3 h / Heating
View Scheme
参考文献
Martin, Dieter; Nadolski, Karin; Gruendemann, Egon
Journal fuer Praktische Chemie (Leipzig), 1984 , vol. 326, # 5 p. 737 - 746
