4-(3-氟-5-羟基苯基)-3,4,5,6-四氢-2H-吡喃-4-羧酸酯乙基合成路线 （共 1 条）
反应条件
1: 61 percent / K2CO3 / dimethylformamide / 120 °C
2: 96 percent / aq. LiOH / methanol; tetrahydrofuran / Heating
3: (COCl)2 / CH2Cl2 / 0 - 20 °C
4: NH3 / CH2Cl2 / 20 °C
View Scheme
参考文献
Mano, Takashi; Stevens, Rodney W.; Nakao, Kazunari; Okumura, Yoshiyuki; Kawamura, Kiyoshi; Ando, Akemi; Matsuoka, Yoko
Synthesis, 2004 , # 16 p. 2625 - 2628
