[3aS-(3aalpha,4beta,6aalpha)]-六氢-2-氧代-1,3-二(苯基甲基)-1H-噻吩并[3,4-d]咪唑-4-戊酸苯甲酯合成路线 (共 1 条)
反应条件
1: With water; hydrogen bromide in xylene 24 h; Heating / reflux; 2: With sodium hydroxide in water pH=12; 3: With hydrogenchloride; trichloromethyl chloroformate; carbon Product distribution / selectivity; more than 3 stages;
参考文献
DSM IP ASSETS B.V.; FUDAN UNIVERSITY
Patent: WO2009/49476 A1, 2009 ;
Location in patent: Page/Page column 38 ;