2-氨基-5-氰基-4-甲基吡啶合成路线 (共 4 条)
反应条件
1: in isobutyramide T=170°C; 24 h; Inert atmosphere; 2: With ethylenediamine in isobutyramide; water 0.25 h;
参考文献
NOVARTIS AG; BETSCHART, Claudia; COTESTA, Simona; HINTERMANN, Samuel; WAGNER, Juergen; ROY, Bernard, Lucien; GERSPACHER, Marc; VON MATT, Anette; BEHNKE, Dirk
Patent: WO2011/73316 A1, 2011 ;
Location in patent: Page/Page column 65 ;
WO 2011/073316 A1
反应条件
in N,N-dimethyl-formamide 20 h; Heating;
参考文献
Dunn; Norrie
Advanced Synthesis and Catalysis, 1996 , vol. 338, # 7 p. 663 - 666
反应条件
dimethylammonium 2,4-dichlorophenoxyacetate; CuCN
参考文献
US2004/77605 A1, ;
US 20040077605 A1
反应条件
in water; N,N-dimethyl-formamide
参考文献
Merck and Co., Inc.
Patent: US5972975 A1, 1999 ;