6-甲氧基-7-苄氧基喹唑啉-4-酮合成路线 （共 34 条）
反应条件
1: K2CO3 / dimethylformamide / 20 °C 2: 100 percent / HNO3; Ac2O / 3 h / 20 °C 3: 97 percent / Fe; FeCl3 / acetic acid; H2O; ethanol / 4 h / 20 °C 4: 87 percent / 5 h / 190 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 46, # 23 p. 4910 - 4925
反应条件
1: potassium carbonate / acetone 2: nitric acid / acetic acid 3: sodium tetrahydroborate; NiII chloride hexahydrate 4: formamide View Scheme
参考文献
Tetrahedron Letters, , vol. 52, # 10 p. 1053 - 1056
反应条件
1: sodium tetrahydroborate; NiII chloride hexahydrate 2: formamide View Scheme
参考文献
Tetrahedron Letters, , vol. 52, # 10 p. 1053 - 1056
反应条件
1: nitric acid / acetic acid 2: sodium tetrahydroborate; NiII chloride hexahydrate 3: formamide View Scheme
参考文献
Tetrahedron Letters, , vol. 52, # 10 p. 1053 - 1056
反应条件
1: potassium carbonate / acetone 2: nitric acid / acetic acid 3: sodium tetrahydroborate; NiII chloride hexahydrate 4: formamide View Scheme
参考文献
Tetrahedron Letters, , vol. 52, # 10 p. 1053 - 1056
反应条件
1.1: oxalyl dichloride / toluene / 2 h / Reflux 1.2: 2 h 2.1: acetic acid / 0.17 h / 90 °C 2.2: 1 h / Reflux 3.1: 1,4-dioxane / 12 h / Reflux 3.2: 3 h / Reflux View Scheme
反应条件
1.1: potassium permanganate / acetone / 2 h / 30 - 50 °C 2.1: oxalyl dichloride / toluene / 2 h / Reflux 2.2: 2 h 3.1: acetic acid / 0.17 h / 90 °C 3.2: 1 h / Reflux 4.1: 1,4-dioxane / 12 h / Reflux 4.2: 3 h / Reflux View Scheme
反应条件
1.1: acetic acid / 0.17 h / 90 °C 1.2: 1 h / Reflux 2.1: 1,4-dioxane / 12 h / Reflux 2.2: 3 h / Reflux View Scheme
反应条件
1.1: nitric acid / 2 h / 0 - 20 °C 2.1: potassium permanganate / acetone / 2 h / 30 - 50 °C 3.1: oxalyl dichloride / toluene / 2 h / Reflux 3.2: 2 h 4.1: acetic acid / 0.17 h / 90 °C 4.2: 1 h / Reflux 5.1: 1,4-dioxane / 12 h / Reflux 5.2: 3 h / Reflux View Scheme
参考文献
Tetrahedron Letters, , vol. 52, # 10 p. 1053 - 1056
