6-甲氧基-7-苄氧基喹唑啉-4-酮合成路线 (共 34 条)
反应条件
hydrogenchloride in diethyl ether; N,N-dimethyl-formamide; mineral oil; Petroleum ether
参考文献
Lambert, Christine Marie Paul; Ple, Patrick
Patent: US2004/63733 A1, 2004 ;
反应条件
1: With sodium hydride in N,N-dimethyl-formamide
1.8 h;
2: With 2,2-Dimethyl-propionic acid chloromethyl ester
T=20°C; 2 h;
参考文献
Zeneca Limited; Zeneca Pharma S. A.
Patent: US6362336 B1, 2002 ;
Location in patent: Example 85 ;
US 6362336 B1
反应条件
thionyl chloride in 1-methyl-pyrrolidin-2-one; dichloromethane; N,N-dimethyl-formamide; mineral oil
参考文献
Lambert, Christine Marie Paul; Ple, Patrick
Patent: US2004/44015 A1, 2004 ;
反应条件
1: SOCl2; DMF / Heating
2: propan-2-ol / 4 h / Heating
View Scheme
参考文献
HANMI HOLDINGS CO., LTD.; BAE, In Hwan; BYUN, Eun Young; JU, Hae Kyoung; SONG, Ji Young; JUNG, Seung Hyun; JUN, Mi Ae; KIM, Ho Seok; JUNG, Young Hee; SHIM, Mi Yon; AHN, Young Gil; KIM, Maeng Sup
Patent: WO2012/30160 A2, 2012 ;