4,5-二(2-甲氧基乙氧基)-2-硝基苯甲酸乙酯合成路线 （共 8 条）
反应条件
sulfuric acid; nitric acid in acetic acid T=20 - 70°C; 2 h;
参考文献
Zhang, Gengzhen; Zha, Linlin
Research on Chemical Intermediates, 2013 , vol. 39, # 6 p. 2303 - 2309
反应条件
conc. HNO3; tetra-(n-butyl)ammonium iodide; potassium carbonate in water; acetic acid; acetone
反应条件
conc. HNO3; tetra-(n-butyl)ammonium iodide in acetic acid; acetone
参考文献
US5747498 A1, ;
US 5747498 A
反应条件
1: potassium carbonate; tetrabutylammonium iodide / acetone / 120 h / Heating 2: acetic acid; nitric acid / 24 h / 20 °C View Scheme
参考文献
Molecules, , vol. 11, # 4 p. 286 - 297
反应条件
1: hydrogen / PtO2*H2O / methanol / 20 °C / 2585.74 Torr 2: 84 percent / 12 h / 165 - 170 °C 3: phosphoryl choride; N,N-diethylaniline / 0.67 h / 70 - 90 °C View Scheme
参考文献
Molecules, , vol. 11, # 4 p. 286 - 297
反应条件
1: hydrogen / PtO2*H2O / methanol / 20 °C / 2585.74 Torr 2: 84 percent / 12 h / 165 - 170 °C View Scheme
参考文献
Li, Shilei; Wang, Xiao; He, Yong; Zhao, Mingxia; Chen, Yurong; Xu, Jingli; Feng, Man; Chang, Jin; Ning, Hongyu; Qi, Chuanmin
European Journal of Medicinal Chemistry, 2013 , vol. 67, p. 293 - 301
反应条件
1: hydrogen / PtO2*H2O / methanol / 20 °C / 2585.74 Torr 2: 84 percent / 12 h / 165 - 170 °C 3: phosphoryl choride; N,N-diethylaniline / 0.67 h / 70 - 90 °C 4: pyridine / propan-2-ol View Scheme
参考文献
LAURUS LABS PRIVATE LIMITED; SIMHADRI, Srinivas; BIRADAR, Arun, Gunwanthrao; INDUKURI, Venkata, Sunil, Kumar; GORANTLA, Seeta, Ramanjaneyulu; CHAVA, Satyanarayana
Patent: WO2013/156835 A1, 2013 ;
反应条件
platinum on carbon; hydrogen in methanol T=20 - 40°C; P=760.051 Torr;
参考文献
Research on Chemical Intermediates, , vol. 39, # 6 p. 2303 - 2309
