2-氨基-4.5-双-(甲氧基乙氧基)苯甲酸乙酯合成路线 （共 9 条）
反应条件
platinum on carbon; hydrogen in methanol T=20 - 40°C; P=760.051 Torr;
参考文献
Research on Chemical Intermediates, , vol. 39, # 6 p. 2303 - 2309
反应条件
1: acetic acid; nitric acid / 24 h / 20 °C 2: hydrogen / PtO2*H2O / methanol / 20 °C / 2585.74 Torr View Scheme
参考文献
Molecules, , vol. 11, # 4 p. 286 - 297
反应条件
1: potassium carbonate; tetrabutylammonium iodide / acetone / 120 h / Heating 2: acetic acid; nitric acid / 24 h / 20 °C 3: hydrogen / PtO2*H2O / methanol / 20 °C / 2585.74 Torr View Scheme
参考文献
Molecules, , vol. 11, # 4 p. 286 - 297
反应条件
1: 84 percent / 12 h / 165 - 170 °C 2: phosphoryl choride; N,N-diethylaniline / 0.67 h / 70 - 90 °C View Scheme
参考文献
Molecules, , vol. 11, # 4 p. 286 - 297
反应条件
ammonium acetate in methanol T=110°C; 6 h;
参考文献
Ube Industries, Ltd.
Patent: EP1650196 A1, 2006 ;
Location in patent: Page/Page column 7 ;
反应条件
in formamide T=160°C; 3 h;
参考文献
Seimbille, Yann; Phelps, Michael E.; Czernin, Johannes; Silverman, Daniel H. S.
Journal of Labelled Compounds and Radiopharmaceuticals, 2005 , vol. 48, # 11 p. 829 - 843
反应条件
T=165 - 170°C; 12 h;
参考文献
Knesl, Petr; Roeseling, Dirk; Jordis, Ulrich
Molecules, 2006 , vol. 11, # 4 p. 286 - 297
反应条件
in 2-methoxy-ethanol T=125°C; 8 h;
参考文献
European Journal of Medicinal Chemistry, , vol. 43, # 7 p. 1478 - 1488
反应条件
1: 84 percent / 12 h / 165 - 170 °C 2: phosphoryl choride; N,N-diethylaniline / 0.67 h / 70 - 90 °C 3: pyridine / propan-2-ol View Scheme
参考文献
Knesl, Petr; Roeseling, Dirk; Jordis, Ulrich
Molecules, 2006 , vol. 11, # 4 p. 286 - 297
