6,7-二甲氧乙氧基喹唑啉-4-酮合成路线 （共 24 条）
反应条件
ammonium acetate in methanol T=110°C; 6 h;
参考文献
Ube Industries, Ltd.
Patent: EP1650196 A1, 2006 ;
Location in patent: Page/Page column 7 ;
反应条件
ammonium acetate in methanol T=95°C; 8 h;
参考文献
Ube Industries, Ltd.
Patent: EP1477481 A1, 2004 ;
Location in patent: Page 19 ;
参考文献
LAURUS LABS PRIVATE LIMITED; SIMHADRI, Srinivas; BIRADAR, Arun, Gunwanthrao; INDUKURI, Venkata, Sunil, Kumar; GORANTLA, Seeta, Ramanjaneyulu; CHAVA, Satyanarayana
Patent: WO2013/156835 A1, 2013 ;
Location in patent: Page/Page column 12; 13 ;
反应条件
1: 4,5-bis(2-methoxyethoxy)-2-nitrobenzonitrile With iron(III) chloride; hydrazine hydrate in methanol; water 3 h; Heating; 2: formic acid With hydrogenchloride in water T=90 - 130°C; Further stages.;
参考文献
Chandregowda, Venkateshappa; Venkateswara Rao, Gudapati; Chandrasekara Reddy, Goukanapalli
Heterocycles, 2007 , vol. 71, # 1 p. 39 - 48
反应条件
1: hydrogen / PtO2*H2O / methanol / 20 °C / 2585.74 Torr 2: 84 percent / 12 h / 165 - 170 °C View Scheme
参考文献
Molecules, , vol. 11, # 4 p. 286 - 297
反应条件
1: potassium carbonate; tetrabutylammonium iodide / acetone / 120 h / Heating 2: acetic acid; nitric acid / 24 h / 20 °C 3: hydrogen / PtO2*H2O / methanol / 20 °C / 2585.74 Torr 4: 84 percent / 12 h / 165 - 170 °C View Scheme
参考文献
Molecules, , vol. 11, # 4 p. 286 - 297
反应条件
1: With ammonium cerium (IV) nitrate; acetic acid in water 2: With sodium hydroxide in water
参考文献
Marzaro, Giovanni; Guiotto, Adriano; Pastorini, Giovanni; Chilin, Adriana
Tetrahedron, 2010 , vol. 66, # 4 p. 962 - 968
反应条件
1: acetic acid; nitric acid / 24 h / 20 °C 2: hydrogen / PtO2*H2O / methanol / 20 °C / 2585.74 Torr 3: 84 percent / 12 h / 165 - 170 °C View Scheme
参考文献
Molecules, , vol. 11, # 4 p. 286 - 297
反应条件
1: With pyridine in isopropyl alcohol T=80°C; 1 h; 2: With hydrogenchloride in 1,4-dioxane; diethyl ether; chloroform T=20°C; 1 h; Product distribution / selectivity;
参考文献
WO2011/76813 A1, ;
Page/Page column 19 ;
反应条件
in formamide T=160°C; 3 h;
参考文献
Seimbille, Yann; Phelps, Michael E.; Czernin, Johannes; Silverman, Daniel H. S.
Journal of Labelled Compounds and Radiopharmaceuticals, 2005 , vol. 48, # 11 p. 829 - 843
