1-(4-氯苯基)-3-二甲氨基-1-丙酮盐酸盐合成路线 （共 13 条）
反应条件
1: aq. ethanol / Heating; 2-3h
2: 1. POCl3, 2. Et3N / 1. CH2Cl2, RT, 24h
View Scheme
参考文献
Sahasrabudhe, S. D.; Tilak, B. D.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1984 , vol. 23, # 10 p. 914 - 917
反应条件
1: aq. ethanol / Heating; 2-3h
2: 1. POCl3, 2. Et3N / 1. CH2Cl2, RT, 24h
View Scheme
参考文献
Sahasrabudhe, S. D.; Tilak, B. D.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1984 , vol. 23, # 10 p. 914 - 917
反应条件
hydrazine in methanol; water
T=50°C; 2 h; Heating / reflux;
参考文献
SOLVAY PHARMACEUTICALS B.V.
Patent: WO2008/34863 A2, 2008 ;
Location in patent: Page/Page column 28-29 ;
WO 2008/034863 A2
