1: 98 percent / meta-chloroperbenzoic acid / CH2Cl2 / 1 h / -70 °C 2: methyllithium / tetrahydrofuran; diethyl ether / 0.33 h / -70 °C 3: tetrahydrofuran; diethyl ether / 0.75 h / -70 °C 4: CCl4 / 0.33 h / Heating View Scheme

in N,N-dimethyl-formamide T=30°C; also in THF; Rate constant;

1: 99.2 percent / H2O2 / acetic acid / 2 h / 100 °C 2: n-butyllithium / 1.) hexane, ethyl ether, -70 deg C, 25 min, 2.) from - 70 deg C up to room temperature in 20 min 3: diethyl ether / 1.) -10 deg C, 2.) reflux 25 min 4: sodium amalgam, disodium hydrogen phosphate / methanol / 1 h / 0 °C View Scheme

1: 99.2 percent / H2O2 / acetic acid / 2 h / 100 °C 2: n-butyllithium / 1.) hexane, ethyl ether, -70 deg C, 25 min, 2.) from - 70 deg C up to room temperature in 20 min 3: diethyl ether / 1.) -10 deg C, 2.) reflux 25 min 4: sodium amalgam, disodium hydrogen phosphate / methanol / 1 h / 0 °C View Scheme

dihydrogen peroxide in acetic acid T=100°C; 2 h;

1: 98 percent / meta-chloroperbenzoic acid / CH2Cl2 / 1 h / -70 °C 2: methyllithium / tetrahydrofuran; diethyl ether / 0.33 h / -70 °C 3: tetrahydrofuran; diethyl ether / 0.75 h / -70 °C 4: CCl4 / 0.33 h / Heating View Scheme

1: 99.2 percent / H2O2 / acetic acid / 2 h / 100 °C 2: n-butyllithium / 1.) hexane, ethyl ether, -70 deg C, 25 min, 2.) from - 70 deg C up to room temperature in 20 min 3: diethyl ether / 1.) -10 deg C, 2.) reflux 25 min 4: sodium amalgam, disodium hydrogen phosphate / methanol / 1 h / 0 °C View Scheme

1: 98 percent / meta-chloroperbenzoic acid / CH2Cl2 / 1 h / -70 °C 2: methyllithium / tetrahydrofuran; diethyl ether / 0.33 h / -70 °C 3: tetrahydrofuran / 25 - 30 °C 4: CCl4 / Heating View Scheme

1: 98 percent / NaIO4 / methanol; H2O / 0 - 20 °C 2: 90 percent / SO2Cl2 / CH2Cl2 / 3.5 h / -78 - 20 °C View Scheme