1,7-二氧螺环-[5,5]十一烷合成路线 （共 40 条）
反应条件
n-butyllithium in tetrahydrofuran T=-78°C;
参考文献
Tetrahedron Letters, , vol. 26, # 4 p. 535 - 538
反应条件
1: 90 percent / hydrochloric acid / H2O / 3 h / Ambient temperature 2: n-butyllithium / tetrahydrofuran; hexane / -78 degC, allowed to warm to room temperature 3: H2 / PtO2 / methanol / 2068.6 Torr 4: hydrochloric acid / methanol / Ambient temperature View Scheme
参考文献
Canadian Journal of Chemistry, , vol. 59, p. 1105 - 1121
反应条件
1: n-butyllithium / tetrahydrofuran; hexane / -78 degC, allowed to warm to room temperature 2: H2 / PtO2 / methanol / 2068.6 Torr 3: hydrochloric acid / methanol / Ambient temperature View Scheme
参考文献
Canadian Journal of Chemistry, , vol. 59, p. 1105 - 1121
反应条件
1: H2 / PtO2 / methanol / 2068.6 Torr 2: hydrochloric acid / methanol / Ambient temperature View Scheme
参考文献
Canadian Journal of Chemistry, , vol. 59, p. 1105 - 1121
反应条件
1: 79 percent / KOH / 12 h / Heating 2: 72 percent / hydroquinone / 144 h / Ambient temperature 3: 93 percent / H2 / PtO2 / diethyl ether / 7 h / 735.5 Torr / Ambient temperature View Scheme
参考文献
Chemische Berichte, , vol. 114, # 4 p. 1418 - 1427
反应条件
1: 72 percent / hydroquinone / 144 h / Ambient temperature 2: 93 percent / H2 / PtO2 / diethyl ether / 7 h / 735.5 Torr / Ambient temperature View Scheme
参考文献
Chemische Berichte, , vol. 114, # 4 p. 1418 - 1427
反应条件
1: 53 percent / Al2O3 / CH2Cl2 / 1) 0 deg C, 15 min, 2) r.t., 8 h, 3) 45 deg C, 9 h 2: 64 percent / NaBH4 / ethanol / 2 h / 0 °C View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 23 p. 3159 - 3160
反应条件
1: 1) potassium diisopropylamide / 1) THF, hexane, -78 deg C, 1.5 h, 2) -78 deg C to r.t. 2: 95 percent / amberlite IR 120, MgSO4 / tetrahydrofuran / 48 h / Heating View Scheme
参考文献
Synthesis, , # 11 p. 1013 - 1019
反应条件
iodine; mercury(II) oxide in cyclohexane 16 h; Heating;
参考文献
Organic and Biomolecular Chemistry, , vol. 2, # 8 p. 1145 - 1154
反应条件
1: 79 percent / calcium chloride / CH2Cl2 / 4 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 42, # 15 p. 4333 - 4342
